Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) for PDB: 8Y2D
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataKi:  38.3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/24/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataKi:  67nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataIC50: 200nMAssay Description:Inhibition of dopamine transporter-mediated [3H]dopamine uptake in Wistar rat striatal synaptosomes by liquid scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataKi:  230nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/22/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataIC50: 460nMAssay Description:Inhibition of [3H]dopamine uptake in HEK cells expressing human DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataKi:  1.77E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM50002316(LARODOPA | SINEMET | 4-(2-Amino-ethyl)-benzene-1,2...)
Affinity DataKi:  1.92E+3nMAssay Description:Inhibition of [3H]dopamine uptake from wild type human DAT expressed in COS-7 cells preincubated for 30 mins followed by [3H]dopamine addition and me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataKi:  3.10E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibitory constant towards reuptake of [125I]-12 from dopamine transporter in rat striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataKi:  5.30E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataKi:  5.90E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/3/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent dopamine transporter(Human)
University of Toronto

Curated by PDSP Ki Database
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataKi:  6.40E+3nMAssay Description:Displacement of [125I]RT155 binding in HEK cells expressing human DATMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)