Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 8YNA
TargetHistamine H4 receptor(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 22542BDBM22542(4-(1H-imidazol-4-ylmethyl)piperidine | 4-(1H-imida...)
In Depth
Date in BDB:
4/25/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistamine H4 receptor(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 22542BDBM22542(4-(1H-imidazol-4-ylmethyl)piperidine | 4-(1H-imida...)
Affinity DataEC50:  15.8nMAssay Description:Agonist activity at human histamine H4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistamine H4 receptor(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 22542BDBM22542(4-(1H-imidazol-4-ylmethyl)piperidine | 4-(1H-imida...)
Affinity DataKi:  19.9nMAssay Description:Displacement of [3H]histamine from human H4 receptor expressed in HEK293 cells after 1 to 1.5 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistamine H4 receptor(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 22542BDBM22542(4-(1H-imidazol-4-ylmethyl)piperidine | 4-(1H-imida...)
Affinity DataKi:  20nMAssay Description:Ligand displacement assays were performed on The SK-N-MC/hH4R cell homogenates. Retained radioactivity was determined by liquid scintillation countin...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/28/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistamine H4 receptor(Human)
The R. W. Johnson Pharmaceutical Research Institute

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 22542BDBM22542(4-(1H-imidazol-4-ylmethyl)piperidine | 4-(1H-imida...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]histamine from human histamine H4 receptor expressed in CHO-K1 cells after 1 hr by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)