Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 9AVR
TargetEukaryotic initiation factor 4A-I(Human)
Infinity Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335583BDBM50335583(silvestrol | CHEMBL555196)
Affinity DataEC50:  0.800nMAssay Description:Inhibition of eIF4FA in human MDA-MB-231 cells transfected with c-myc- 5'-UTR-luciferase construct assessed as reduction in translation initiation in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEukaryotic initiation factor 4A-I(Human)
Infinity Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50335583BDBM50335583(silvestrol | CHEMBL555196)
Affinity DataEC50:  7nMAssay Description:Inhibition of eIF4FA in human MDA-MB-231 cells transfected with tubulin 5'-UTR-luciferase construct assessed as reduction in translation initiation i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)