Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 9AYL
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Rat)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452245BDBM50452245(Act-709478)
Affinity DataIC50: 13nMAssay Description:Inhibition of Cav3.2 in rat assessed as decrease in calcium flux preincubated for 3 mins followed by CaCl2 addition by Fluo-4-AM dye-based FLIPR assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Human)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452245BDBM50452245(Act-709478)
Affinity DataIC50: 18nMAssay Description:Inhibition of recombinant Cav3.2 (unknown origin) expressed in HEK293 cells assessed as decrease in calcium flux preincubated for 3 mins followed by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetVoltage-dependent T-type calcium channel subunit alpha-1H(Mouse)
Idorsia Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50452245BDBM50452245(Act-709478)
Affinity DataIC50: 40nMAssay Description:Inhibition of Cav3.2 in mouse assessed as decrease in calcium flux preincubated for 3 mins followed by CaCl2 addition by Fluo-4-AM dye-based FLIPR as...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)