Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 9BFK
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067207BDBM50067207(CHEMBL3304438)
Affinity DataIC50: 72nMAssay Description:Inhibition of [3H]choline uptake at human choline transporter expressed in HEK293 cells preincubated for 15 mins followed by [3H]choline addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/11/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067207BDBM50067207(CHEMBL3304438)
Affinity DataIC50: 90nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 10 uM [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHigh affinity choline transporter 1(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067207BDBM50067207(CHEMBL3304438)
Affinity DataIC50: 270nMAssay Description:Inhibition of human CHT Leu530Ala and Val531Ala mutant expressed in HEK293 cells assessed as remaining transporter activity in presence of 100 nM [3H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)