Compile Data Set for Download or QSAR
Report error Found 89 Enz. Inhib. hit(s) for PDB: 9BJK
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataIC50: 0.00400nMAssay Description:Concentration for 50% inhibition of [3H]naloxone (1 M) binding to opioid receptor in rat brain membrane was determined in the presence of NaClMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataIC50: 0.00900nMAssay Description:Concentration for 50% inhibition of [3H]naloxone (1 M) binding to opioid receptor in rat brain membrane was determined in the absence of NaClMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  0.230nMAssay Description:Antagonist activity at human mu-opioid receptor expressed in CHO cells assessed as inhibition of DAMGO-induced [35S]GTPgammaS binding after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  0.310nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKd:  0.400nMAssay Description:Opioid receptor mu 1 affinity against the receptor site model site 1 (mu1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKd:  0.400nMAssay Description:Opioid receptor mu 1 affinity against the receptor site model site 1 (mu1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  0.559nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  0.562nMAssay Description:Displacement of [3H]DPN from human recombinant mu-type opioid receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  0.570nMAssay Description:Displacement of [125I]-IBOxyA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  0.660nMAssay Description:Activity at human cloned mu opioid receptor expressed in CHO cells by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Mouse)
Memorial Sloan-Kettering Cancer Center

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  0.670nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  0.680nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in guinea pig brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  0.680nMAssay Description:Affinity to mu-receptor, using [3H]DAMGO as radioligand in homogenates of guinea pig brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  0.790nMAssay Description:Agonist activity at human opioid gamma receptor expressed in CHO cells assessed as inhibition of DAGO-stimulated [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  0.900nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  0.930nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  0.980nMAssay Description:Binding affinity to human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  1nMAssay Description:Binding affinity to mu-opioid receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKd:  1nMAssay Description:Displacement of [3H]-(-)-naloxone from opiate receptor in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  1.10nMAssay Description:The ability to displace [3H]-naloxone from the Opioid receptor mu isolated from rat brain membrane.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  1.10nMAssay Description:In vivo binding affinity against mu opioid receptor was measured by using labeled ligand [3H]naloxone (0.5 nM)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  1.10nMAssay Description:Displacement of 2-((1E,3E,5E)-5-(1-Ethyl-3,3-dimethyl-5-sulfoindolin-2-ylidene)-penta-1,3-dien-1-yl)-1-(6-((6-((6S,7R,7aR,12bS)-9-hydroxy-7-methoxy-3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]DAMGO from human MOR expressed in HEK293 cells preincubated for 1 hr followed by radioligand addition measured after 1 hr by liqu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/26/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  1.35nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2011
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  1.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2011
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  1.40nMAssay Description:Inhibition of [3H]DAMGO binding to rat Opioid receptor mu 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of [3H]-Naloxone binding to rat brain membrane without NaClMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2018
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  1.40nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  1.5nMAssay Description:Binding affinity to mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  1.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataEC50:  1.5nMAssay Description:Binding affinity to rat brain opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataIC50: 1.60nMAssay Description:Inhibitory concentration against human Adenosine A3 receptor expressed in HEK293 cells using 0.1 nM [3H]AB-MECAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]DAGO from mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataIC50: 2nMAssay Description:Binding affinity against mu-opiate receptor (human) using [3H]DAMGO radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/25/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]naloxone binding to opioid receptor in presence of NaClMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataIC50: 2nMAssay Description:Inhibition of [3H]naloxone binding to opioid receptor in presence of NaClMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-naloxone from rat mu opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in guinea pig brain membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]-DAMGO from mu opioid receptor in guinea pig brain membrane after 120 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]-DAMGO from MOR in guinea pig brain membranes measured by competitive radioligand receptor binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 54795BDBM54795((4R,4aS,7aR,12bS)-4a,9-bis(oxidanyl)-3-prop-2-enyl...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]DAMGO from mu-type opioid receptor in guinea pig brain membranes after 120 mins by solid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]-naloxone from human mu opioid receptor expressed in CHO-K1 cells by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [125I]-IBNalA from MOR-1 expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/8/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]DAMGO from MOR in guinea pig brain membranes after 120 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Guinea pig)
Institut F£R Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  2.34nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2011
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKd:  3nMAssay Description:Inhibition against binding of radioligand [N-allyl-2-3-3H]-naloxone to membrane of baby hamster kidney cells infected with forest virus encoding the ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Bovine)
Stanford University

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  3.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2011
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  3.60nMAssay Description:In vitro binding affinity to human Opioid receptor mu 1 on CHO cell membranes using [3H]diprenorphine displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/27/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Harvard Medical School

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  3.70nMAssay Description:Antagonist activity against human cloned mu opioid receptor expressed in CHO cells assessed as inhibition of loperamide-stimulated [35S]GTP-gamma-S b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000788BDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity towards mu-opioid receptor by displacement of [3H]NAL at 10 nM from rat brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
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