Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) for PDB: 9ERX
TargetCannabinoid receptor 1(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067499BDBM50067499((6aR,10aR)-3-(1,1-dimethyl-heptyl)-9-hydroxymethyl...)
Affinity DataKi:  0.0600nMAssay Description:Binding affinity to CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067499BDBM50067499((6aR,10aR)-3-(1,1-dimethyl-heptyl)-9-hydroxymethyl...)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Rat)
Saint Louis University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067499BDBM50067499((6aR,10aR)-3-(1,1-dimethyl-heptyl)-9-hydroxymethyl...)
Affinity DataKi:  0.230nMAssay Description:Displacement of [3H]CP-55940 binding to Cannabinoid receptor 1 in rat brain membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067499BDBM50067499((6aR,10aR)-3-(1,1-dimethyl-heptyl)-9-hydroxymethyl...)
Affinity DataEC50:  0.600nMAssay Description:Potency at human CB1 receptor in a [35S]GTP-gamma-S functional assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Rat)
Saint Louis University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067499BDBM50067499((6aR,10aR)-3-(1,1-dimethyl-heptyl)-9-hydroxymethyl...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to rat CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Rat)
Saint Louis University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067499BDBM50067499((6aR,10aR)-3-(1,1-dimethyl-heptyl)-9-hydroxymethyl...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to rat CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067499BDBM50067499((6aR,10aR)-3-(1,1-dimethyl-heptyl)-9-hydroxymethyl...)
Affinity DataKi:  0.730nMAssay Description:Binding affinity to human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Rat)
Saint Louis University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067499BDBM50067499((6aR,10aR)-3-(1,1-dimethyl-heptyl)-9-hydroxymethyl...)
Affinity DataKi:  0.730nMAssay Description:Binding affinity for the Cannabinoid receptor using [3H]CP-55940 as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1/2(Human)TBA
LigandChemical structure of BindingDB Monomer ID 50067499BDBM50067499((6aR,10aR)-3-(1,1-dimethyl-heptyl)-9-hydroxymethyl...)
Affinity DataKi:  0.730nMAssay Description:The affinity of compound for the cannabinoid brain receptor was determined by measuring its ability to displace [3H]CP-55940 from its binding site in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/5/2018
Entry Details
PDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067499BDBM50067499((6aR,10aR)-3-(1,1-dimethyl-heptyl)-9-hydroxymethyl...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]CP-55940 form human recombinant CB1 receptor expressed in HEK293 cells by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Rat)
Saint Louis University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067499BDBM50067499((6aR,10aR)-3-(1,1-dimethyl-heptyl)-9-hydroxymethyl...)
Affinity DataKi:  2.75nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in rat cerebellumMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067499BDBM50067499((6aR,10aR)-3-(1,1-dimethyl-heptyl)-9-hydroxymethyl...)
Affinity DataKi:  2.94nM ΔG°:  -49.5kJ/molepH: 7.4 T: 2°CAssay Description:The Kd of CP 55,940 in the isolated CB1 and CB2 receptor expressing membranes was previously determined to be 2.3 nM and 1.5 nM, respectively (see Pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/3/2017
Entry Details
US Patent
PDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Rat)
Saint Louis University School of Medicine

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067499BDBM50067499((6aR,10aR)-3-(1,1-dimethyl-heptyl)-9-hydroxymethyl...)
Affinity DataEC50:  5nMAssay Description:Displacement of [35S]GTP-gamma-S from rat cerebellar CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067499BDBM50067499((6aR,10aR)-3-(1,1-dimethyl-heptyl)-9-hydroxymethyl...)
Affinity DataKi:  18.6nMAssay Description:Displacement of [3H]SR141716A from human CB1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067499BDBM50067499((6aR,10aR)-3-(1,1-dimethyl-heptyl)-9-hydroxymethyl...)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human recombinant cannabinoid CB1 receptor expressed in MMY23 Saccharomyces cerevisiae assessed as degradation of FDGlu to fluore...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)