Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 9FB2
TargetLysosomal acid glucosylceramidase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639868BDBM50639868(CHEMBL5562071)
Affinity DataKd:  50nMAssay Description:Binding affinity to human Avi/10-his tagged GCase (40 to 536 residues) expressed baculovirus expression system in Sf9 cells in assessed as dissociati...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetLysosomal acid glucosylceramidase(Human)
Astex Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50639868BDBM50639868(CHEMBL5562071)
Affinity DataEC50:  9.00E+3nMAssay Description:Positive allosteric modulation of GCase in human Fibroblast cells using GBA1-FQ2 as substrate preincubated for 24 hrs followed by substrate addition ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)