Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 9HUE
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102692BDBM50102692(ORG-25543 | 4-Benzyloxy-N-(1-dimethylamino-cyclope...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant human GlyT2a expressed in Xenopus laevis oocytes assessed as reduction in channel current by two-electrode voltage clamp el...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102692BDBM50102692(ORG-25543 | 4-Benzyloxy-N-(1-dimethylamino-cyclope...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human GlyT2 stably expressed in CHO cells assessed as reduction in [3H]glycine uptake incubated for 10 mins by liquid scintillation cou...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102692BDBM50102692(ORG-25543 | 4-Benzyloxy-N-(1-dimethylamino-cyclope...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human GlyT-2 expressed in CHO cells assessed as reduction in [3H]-glycine uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102692BDBM50102692(ORG-25543 | 4-Benzyloxy-N-(1-dimethylamino-cyclope...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human Glycine Transporter type-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium- and chloride-dependent glycine transporter 2(Human)
University of Sydney

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50102692BDBM50102692(ORG-25543 | 4-Benzyloxy-N-(1-dimethylamino-cyclope...)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant human GlyT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)