Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) for PDB: 9J87
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82087BDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  4.80nMAssay Description:Affinity against 5-hydroxytryptamine 2A receptor (D) labeled with [125I]DOI.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerotonin 2 (5-HT2) receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82087BDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  4.80nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor using [3H]- 1-(4-bromo-2,5-dimethoxy-phenyl)-2-aminopropane (D) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerotonin 2 (5-HT2) receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82087BDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  14nMAssay Description:Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 receptor binding site by using [3H]- DOB as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerotonin 2 (5-HT2) receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82087BDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  14nMAssay Description:Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 receptor binding site by using [3H]- DOB as a radioligand.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82087BDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  38nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82087BDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  61.6nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Rat)
University of Toronto

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 82087BDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  92nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Rat)
University of Toronto

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 82087BDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  141nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Rat)
University of Toronto

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 82087BDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  215nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82087BDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  300nMAssay Description:Affinity against 5-hydroxytryptamine 2A receptor (K) labeled with [3H]ketanserin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerotonin 2 (5-HT2) receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82087BDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  302nMAssay Description:Binding affinity against 5-hydroxytryptamine 2 receptor using [3H]ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerotonin 2 (5-HT2) receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82087BDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  305nMAssay Description:Binding affinity towards 5-hydroxytryptamine 2 receptor using [3H]- ketanserin as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Rat)
University of Toronto

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 82087BDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  647nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerotonin 2 (5-HT2) receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82087BDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  690nMAssay Description:Binding affinity to 5-hydroxytryptamine 2 receptor in rat frontal cortical membranes by [3H]- KET displacement.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Human)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82087BDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  724nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 82087BDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  923nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2012
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetSerotonin 2 (5-HT2) receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82087BDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  1.02E+3nMAssay Description:Displacement of [3H]ketanserin from 5-hydroxytryptamine 2 receptor of rat frontal cortex homogenateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerotonin 2 (5-HT2) receptor(Rat)
Virginia Commonwealth University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82087BDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  2.57E+3nMAssay Description:Binding affinity to rat cortical membranes at 5-hydroxytryptamine 2 (5-HT2) receptor using [3H]KET as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 2A(Rat)
University of Toronto

Curated by PDSP Ki Database
LigandChemical structure of BindingDB Monomer ID 82087BDBM82087(tryptamine, 5-Methoxy | 5-Methoxytryptamine hydroc...)
Affinity DataKi:  3.79E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/17/2012
Entry Details
PubMedPDB3D3D Structure (crystal)