Compile Data Set for Download or QSAR
maximum 50k data
Found 26 Enz. Inhib. hit(s) with all data for entry = 50008834
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077669((S)-2-Benzyl-N-[(S)-1-((1S,2R,3S)-1-cyclohexylmeth...)
Affinity DataIC50:  0.0250nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077678((3R,4R)-3-(1,4-Dimethoxy-naphthalen-2-ylmethoxy)-4...)
Affinity DataIC50:  0.0600nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077688((3R,4R)-4-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phe...)
Affinity DataIC50:  1.5nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077689((3R,4R)-4-[4-(3-Benzyloxy-propoxy)-phenyl]-3-(naph...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077682(Benzoic acid 2-{4-[(3R,4R)-3-(naphthalen-2-ylmetho...)
Affinity DataIC50:  26nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077671((3R,4R)-3-(Naphthalen-2-ylmethoxy)-4-[4-(3-phenyl-...)
Affinity DataIC50:  41nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077690((3R,4R)-4-[4-(2-Benzyloxy-ethoxy)-phenyl]-3-(napht...)
Affinity DataIC50:  53nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077679(Benzoic acid 4-[(3R,4R)-3-(naphthalen-2-ylmethoxy)...)
Affinity DataIC50:  55nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077685(3-Methoxy-benzoic acid 4-[(3R,4R)-3-(naphthalen-2-...)
Affinity DataIC50:  87nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077691((3R,4R)-4-[4-(2-Benzyloxy-ethoxymethyl)-phenyl]-3-...)
Affinity DataIC50:  91nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077667((3R,4R)-4-[4-(4-Benzyloxy-butoxy)-phenyl]-3-(napht...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077676((3R,4R)-3-(Naphthalen-2-ylmethoxy)-4-[4-(2-phenoxy...)
Affinity DataIC50:  160nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077673((3R,4R)-3-(Naphthalen-2-ylmethoxy)-4-[4-(2-pheneth...)
Affinity DataIC50:  160nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077677(2-(3-{4-[(3R,4R)-3-(Naphthalen-2-ylmethoxy)-piperi...)
Affinity DataIC50:  210nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077666(4-{4-[(3R,4R)-3-(Naphthalen-2-ylmethoxy)-piperidin...)
Affinity DataIC50:  220nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077668((3R,4R)-3-(Naphthalen-2-ylmethoxy)-4-[4-(4-phenoxy...)
Affinity DataIC50:  220nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077680((3R,4R)-3-(Naphthalen-2-ylmethoxy)-4-[4-(3-phenoxy...)
Affinity DataIC50:  540nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077684(CHEMBL283237 | Nicotinic acid 2-{4-[(3R,4R)-3-(nap...)
Affinity DataIC50:  580nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077687((3R,4R)-4-[4-(3-Benzyloxy-propoxymethyl)-phenyl]-3...)
Affinity DataIC50:  740nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077675(3-(5-{4-[(3R,4R)-3-(Naphthalen-2-ylmethoxy)-piperi...)
Affinity DataIC50:  880nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077674(CHEMBL431689 | N-(2-{4-[(3R,4R)-3-(Naphthalen-2-yl...)
Affinity DataIC50:  2.60E+3nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077686((3R,4R)-4-(4-Chloro-phenyl)-3-(4-methoxy-benzyloxy...)
Affinity DataIC50:  2.60E+4nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077672(CHEMBL286733 | N-{4-[(3R,4R)-3-(Naphthalen-2-ylmet...)
Affinity DataIC50:  4.00E+4nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077683(4-(4-Chloro-phenyl)-3-(4-methoxy-benzyloxy)-piperi...)
Affinity DataIC50:  5.00E+4nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077681(4-Methoxy-N-{4-[(3R,4R)-3-(naphthalen-2-ylmethoxy)...)
Affinity DataIC50: >1.00E+6nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50077670((3S,4S)-4-(4-Chloro-phenyl)-3-(4-methoxy-benzyloxy...)
Affinity DataIC50:  1.20E+6nMAssay Description:In vitro inhibitory activity against purified recombinant human reninMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed