Compile Data Set for Download or QSAR
maximum 50k data
Found 37 Enz. Inhib. hit(s) with all data for entry = 50010866
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099465((R)-1-[4-(4-Fluoro-phenoxy)-benzyl]-2-oxo-imidazol...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099466((R)-1-[4-(Naphthalen-2-yloxy)-benzyl]-2-oxo-imidaz...)
Affinity DataIC50:  4nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182((2R,4S)-4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrr...)
Affinity DataIC50:  7nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099465((R)-1-[4-(4-Fluoro-phenoxy)-benzyl]-2-oxo-imidazol...)
Affinity DataIC50:  28nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182((2R,4S)-4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrr...)
Affinity DataIC50:  39nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099466((R)-1-[4-(Naphthalen-2-yloxy)-benzyl]-2-oxo-imidaz...)
Affinity DataIC50:  56nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099466((R)-1-[4-(Naphthalen-2-yloxy)-benzyl]-2-oxo-imidaz...)
Affinity DataIC50:  59nMAssay Description:Inhibition of Matrix metalloproteinase-2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099465((R)-1-[4-(4-Fluoro-phenoxy)-benzyl]-2-oxo-imidazol...)
Affinity DataIC50:  62nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182((2R,4S)-4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrr...)
Affinity DataIC50:  82nMAssay Description:Inhibition of Matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099469((4R)-1-[4-(benzyloxy)benzyl]-N-hydroxy-2-oxoimidaz...)
Affinity DataIC50:  123nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089187((2R,4S)-4-(4'-fluoro-1,1'-biphenyl-4-yl)-N-hydroxy...)
Affinity DataIC50:  182nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099467((4R)-1-[3-(4-fluorophenoxy)benzyl]-N-hydroxy-2-oxo...)
Affinity DataIC50:  214nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099464((R)-1-(4-Methoxy-benzyl)-2-oxo-imidazolidine-4-car...)
Affinity DataIC50:  281nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099470((R)-1-(4'-Fluoro-biphenyl-4-ylmethyl)-2-oxo-imidaz...)
Affinity DataIC50:  331nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099464((R)-1-(4-Methoxy-benzyl)-2-oxo-imidazolidine-4-car...)
Affinity DataIC50:  388nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182((2R,4S)-4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrr...)
Affinity DataIC50:  700nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099468((4R)-N-hydroxy-1-[4-(1-naphthyloxy)benzyl]-2-oxoim...)
Affinity DataIC50:  825nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099466((R)-1-[4-(Naphthalen-2-yloxy)-benzyl]-2-oxo-imidaz...)
Affinity DataIC50:  940nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089185((2R,4S)-4-[4-(benzyloxy)phenyl]-N-hydroxy-5-oxopyr...)
Affinity DataIC50:  946nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099465((R)-1-[4-(4-Fluoro-phenoxy)-benzyl]-2-oxo-imidazol...)
Affinity DataIC50:  1.38E+3nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089188((2R,4S)-N-hydroxy-4-(4-methoxyphenyl)-5-oxopyrroli...)
Affinity DataIC50:  1.48E+3nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089182((2R,4S)-4-[4-(4-Fluoro-phenoxy)-phenyl]-5-oxo-pyrr...)
Affinity DataIC50:  1.56E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099463((4R)-N-hydroxy-1-(2-naphthylmethyl)-2-oxoimidazoli...)
Affinity DataIC50:  1.59E+3nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089186((2R,4S)-N-hydroxy-4-(2-naphthyl)-5-oxopyrrolidine-...)
Affinity DataIC50:  3.45E+3nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099471((2R,4S)-4-[3-(4-fluorophenoxy)phenyl]-N-hydroxy-5-...)
Affinity DataIC50:  4.76E+3nMAssay Description:Inhibition of Matrix metalloproteinase-13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099465((R)-1-[4-(4-Fluoro-phenoxy)-benzyl]-2-oxo-imidazol...)
Affinity DataIC50:  5.45E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089187((2R,4S)-4-(4'-fluoro-1,1'-biphenyl-4-yl)-N-hydroxy...)
Affinity DataIC50:  6.43E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099468((4R)-N-hydroxy-1-[4-(1-naphthyloxy)benzyl]-2-oxoim...)
Affinity DataIC50:  8.02E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089188((2R,4S)-N-hydroxy-4-(4-methoxyphenyl)-5-oxopyrroli...)
Affinity DataIC50:  8.04E+3nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099466((R)-1-[4-(Naphthalen-2-yloxy)-benzyl]-2-oxo-imidaz...)
Affinity DataIC50:  1.27E+4nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099470((R)-1-(4'-Fluoro-biphenyl-4-ylmethyl)-2-oxo-imidaz...)
Affinity DataIC50:  2.59E+4nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089186((2R,4S)-N-hydroxy-4-(2-naphthyl)-5-oxopyrrolidine-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099471((2R,4S)-4-[3-(4-fluorophenoxy)phenyl]-N-hydroxy-5-...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099463((4R)-N-hydroxy-1-(2-naphthylmethyl)-2-oxoimidazoli...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50089185((2R,4S)-4-[4-(benzyloxy)phenyl]-N-hydroxy-5-oxopyr...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099467((4R)-1-[3-(4-fluorophenoxy)benzyl]-N-hydroxy-2-oxo...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50099469((4R)-1-[4-(benzyloxy)benzyl]-N-hydroxy-2-oxoimidaz...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Matrix metalloproteinase-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed