Compile Data Set for Download or QSAR
maximum 50k data
Found 48 Enz. Inhib. hit(s) with all data for entry = 50010977
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100934(CHEMBL40151 | N-[2-(4,4-Dimethyl-2,5-dioxo-imidazo...)
Affinity DataIC50:  1nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100932(CHEMBL416421 | N-{2-(4,4-Dimethyl-2,5-dioxo-imidaz...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100925(CHEMBL38868 | N-[2-(4,4-Dimethyl-2,5-dioxo-imidazo...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100927((S)-N-(1-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100924(CHEMBL41408 | N-Hydroxy-N-[1-(4'-methoxy-biphenyl-...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100922(CHEMBL43411 | N-[2-(4,4-Dimethyl-2,5-dioxo-imidazo...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100918(CHEMBL41102 | N-[1-(4'-Cyano-biphenyl-4-yloxymethy...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100938(CHEMBL42970 | N-[1-(4'-Butyl-biphenyl-4-yloxymethy...)
Affinity DataIC50:  16nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100931(CHEMBL41324 | N-Hydroxy-N-[1-(4'-methyl-biphenyl-4...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100930(CHEMBL39566 | N-[2-(4,4-Dimethyl-2,5-dioxo-imidazo...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100929(CHEMBL39601 | N-[2-(4,4-Dimethyl-2,5-dioxo-imidazo...)
Affinity DataIC50:  26nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100927((S)-N-(1-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)...)
Affinity DataIC50:  42nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100926(CHEMBL285296 | N-[2-(4,4-Dimethyl-2,5-dioxo-imidaz...)
Affinity DataIC50:  48nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100902(CHEMBL288067 | N-[1-(4'-Cyano-biphenyl-4-yloxymeth...)
Affinity DataIC50:  58nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100936(CHEMBL38299 | N-Hydroxy-N-[2-(3,4,4-trimethyl-2,5-...)
Affinity DataIC50:  61nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100921(CHEMBL40613 | N-[1-(4-Furan-2-yl-phenoxymethyl)-2-...)
Affinity DataIC50:  85nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100920(CHEMBL288385 | N-[1-(Biphenyl-4-yloxymethyl)-2-(3,...)
Affinity DataIC50:  89nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100927((S)-N-(1-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)...)
Affinity DataIC50:  120nMAssay Description:Inhibition of matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100935(CHEMBL40335 | N-Hydroxy-N-[1-(4-thiophen-2-yl-phen...)
Affinity DataIC50:  130nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(CHEMBL41943 | N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imi...)
Affinity DataIC50:  180nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100924(CHEMBL41408 | N-Hydroxy-N-[1-(4'-methoxy-biphenyl-...)
Affinity DataIC50:  440nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100930(CHEMBL39566 | N-[2-(4,4-Dimethyl-2,5-dioxo-imidazo...)
Affinity DataIC50:  840nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100934(CHEMBL40151 | N-[2-(4,4-Dimethyl-2,5-dioxo-imidazo...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100920(CHEMBL288385 | N-[1-(Biphenyl-4-yloxymethyl)-2-(3,...)
Affinity DataIC50:  1.10E+3nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(CHEMBL41943 | N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imi...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of matrix metalloproteinase-9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100928(CHEMBL39921 | N-[1-(3'-Cyano-biphenyl-4-yloxymethy...)
Affinity DataIC50:  1.30E+3nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100931(CHEMBL41324 | N-Hydroxy-N-[1-(4'-methyl-biphenyl-4...)
Affinity DataIC50:  1.60E+3nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100921(CHEMBL40613 | N-[1-(4-Furan-2-yl-phenoxymethyl)-2-...)
Affinity DataIC50:  1.60E+3nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100918(CHEMBL41102 | N-[1-(4'-Cyano-biphenyl-4-yloxymethy...)
Affinity DataIC50:  2.10E+3nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100902(CHEMBL288067 | N-[1-(4'-Cyano-biphenyl-4-yloxymeth...)
Affinity DataIC50:  2.30E+3nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(CHEMBL41943 | N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imi...)
Affinity DataIC50:  3.10E+3nMAssay Description:Inhibition of Matrix metalloproteinase-3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100935(CHEMBL40335 | N-Hydroxy-N-[1-(4-thiophen-2-yl-phen...)
Affinity DataIC50:  3.60E+3nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100927((S)-N-(1-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)...)
Affinity DataIC50:  4.60E+3nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100926(CHEMBL285296 | N-[2-(4,4-Dimethyl-2,5-dioxo-imidaz...)
Affinity DataIC50:  4.90E+3nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100922(CHEMBL43411 | N-[2-(4,4-Dimethyl-2,5-dioxo-imidazo...)
Affinity DataIC50:  8.60E+3nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100925(CHEMBL38868 | N-[2-(4,4-Dimethyl-2,5-dioxo-imidazo...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(CHEMBL41943 | N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imi...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Matrix metalloproteinase-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100937(CHEMBL418437 | N-[1-(4'-Cyano-biphenyl-3-yloxymeth...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100933(CHEMBL41150 | N-Hydroxy-N-[1-(4-pyridin-3-yl-pheno...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100937(CHEMBL418437 | N-[1-(4'-Cyano-biphenyl-3-yloxymeth...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100936(CHEMBL38299 | N-Hydroxy-N-[2-(3,4,4-trimethyl-2,5-...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100938(CHEMBL42970 | N-[1-(4'-Butyl-biphenyl-4-yloxymethy...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100933(CHEMBL41150 | N-Hydroxy-N-[1-(4-pyridin-3-yl-pheno...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-2.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100932(CHEMBL416421 | N-{2-(4,4-Dimethyl-2,5-dioxo-imidaz...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrilysin(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100927((S)-N-(1-(4,4-dimethyl-2,5-dioxoimidazolidin-1-yl)...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Matrix metalloproteinase-7More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100929(CHEMBL39601 | N-[2-(4,4-Dimethyl-2,5-dioxo-imidazo...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100928(CHEMBL39921 | N-[1-(3'-Cyano-biphenyl-4-yloxymethy...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50100923(CHEMBL41943 | N-[(R)-2-(4,4-Dimethyl-2,5-dioxo-imi...)
Affinity DataIC50: >1.00E+4nMAssay Description:In vitro inhibition of human Matrix metalloproteinase-1.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed