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Found 18 Enz. Inhib. hit(s) with all data for entry = 50013018
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50125433(1-[2-(4-Benzyl-phenoxy)-ethyl]-1H-imidazo[4,5-b]py...)
Affinity DataIC50:  0.800nMAssay Description:In vitro inhibition of recombinant human leukotriene A4 hydrolase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50125435(1-[2-(4-Benzyl-phenoxy)-ethyl]-1H-imidazo[4,5-b]py...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibition of recombinant human leukotriene A4 hydrolase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50125420(5-[2-(4-Benzyl-phenoxy)-ethyl]-5H-imidazo[4,5-c]py...)
Affinity DataIC50:  11nMAssay Description:In vitro inhibition of recombinant human leukotriene A4 hydrolase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50085279(1-[2-(4-Benzyl-phenoxy)-ethyl]-pyrrolidine | 1-[2-...)
Affinity DataIC50:  26nMAssay Description:In vitro inhibition of recombinant human leukotriene A4 hydrolase.More data for this Ligand-Target Pair
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50125429(1-[2-(4-Benzyl-phenoxy)-ethyl]-1H-imidazo[4,5-c]py...)
Affinity DataIC50:  31nMAssay Description:In vitro inhibition of recombinant human leukotriene A4 hydrolase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50125421(3-[2-(4-Benzyl-phenoxy)-ethyl]-3H-imidazo[4,5-c]py...)
Affinity DataIC50:  36nMAssay Description:In vitro inhibition of recombinant human leukotriene A4 hydrolase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50125426(3-[2-(4-Benzyl-phenoxy)-ethyl]-3H-purine | CHEMBL1...)
Affinity DataIC50:  40nMAssay Description:In vitro inhibition of recombinant human leukotriene A4 hydrolase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50125427(7-[2-(4-Benzyl-phenoxy)-ethyl]-7H-purine | CHEMBL1...)
Affinity DataIC50:  47nMAssay Description:In vitro inhibition of recombinant human leukotriene A4 hydrolase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50125432(1-[2-(4-Benzyl-phenoxy)-ethyl]-1H-imidazo[4,5-c]py...)
Affinity DataIC50:  82nMAssay Description:In vitro inhibition of recombinant human leukotriene A4 hydrolase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50125425(1-[2-(4-Benzyl-phenoxy)-ethyl]-1H-imidazole | CHEM...)
Affinity DataIC50:  120nMAssay Description:In vitro inhibition of recombinant human leukotriene A4 hydrolase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50125423(1-[2-(4-Benzyl-phenoxy)-ethyl]-1H-imidazo[4,5-c]py...)
Affinity DataIC50:  120nMAssay Description:In vitro inhibition of recombinant human leukotriene A4 hydrolase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50125431(4-[2-(4-Benzyl-phenoxy)-ethyl]-4H-imidazo[4,5-b]py...)
Affinity DataIC50:  140nMAssay Description:In vitro inhibition of recombinant human leukotriene A4 hydrolase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50125419(1-[2-(4-Benzyl-phenoxy)-ethyl]-1H-purine | CHEMBL1...)
Affinity DataIC50:  180nMAssay Description:In vitro inhibition of recombinant human leukotriene A4 hydrolase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50125430(3-[2-(4-Benzyl-phenoxy)-ethyl]-3,4-dihydro-imidazo...)
Affinity DataIC50:  500nMAssay Description:In vitro inhibition of recombinant human leukotriene A4 hydrolase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50125424(3-[2-(4-Benzyl-phenoxy)-ethyl]-3H-imidazo[4,5-c]py...)
Affinity DataIC50:  560nMAssay Description:In vitro inhibition of recombinant human leukotriene A4 hydrolase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50125434(9-[2-(4-Benzyl-phenoxy)-ethyl]-9H-purine | CHEMBL1...)
Affinity DataIC50:  730nMAssay Description:In vitro inhibition of recombinant human leukotriene A4 hydrolase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50125428(1-[2-(4-Benzyl-phenoxy)-ethyl]-1H-benzoimidazole |...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibition of recombinant human leukotriene A4 hydrolase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene A-4 hydrolase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50125422(3-[2-(4-Benzyl-phenoxy)-ethyl]-3H-imidazo[4,5-b]py...)
Affinity DataIC50: >3.00E+3nMAssay Description:In vitro inhibition of recombinant human leukotriene A4 hydrolase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed