Compile Data Set for Download or QSAR
maximum 50k data
Found 71 Enz. Inhib. hit(s) with all data for entry = 50015122
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151740((3S,4R)-3-Hydroxy-4-(4''-methyl-biphenyl-4-sulfony...)
Affinity DataIC50:  0.390nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151751(3-Hydroxy-4-(3''-methyl-biphenyl-4-sulfonyl)-tetra...)
Affinity DataIC50:  0.430nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151734((3S,4R)-4-[4-(4-Chloro-benzyloxy)-benzenesulfonyl]...)
Affinity DataIC50:  0.880nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151732(4-[4-(2,4-Dichloro-benzyloxy)-benzenesulfonyl]-3-h...)
Affinity DataIC50:  0.950nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151732(4-[4-(2,4-Dichloro-benzyloxy)-benzenesulfonyl]-3-h...)
Affinity DataIC50:  0.950nMAssay Description:Inhibition of matrix metalloprotease 12More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151736(3-Hydroxy-4-(4-p-tolyloxy-benzenesulfonyl)-tetrahy...)
Affinity DataIC50:  1nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151741((3S,4R)-3-Hydroxy-4-(4-m-tolyloxy-benzenesulfonyl)...)
Affinity DataIC50:  1.10nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151738(3-Hydroxy-4-[4-(4-methyl-benzyloxy)-benzenesulfony...)
Affinity DataIC50:  1.30nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151746(4-[4-(3-Chloro-benzyloxy)-benzenesulfonyl]-3-hydro...)
Affinity DataIC50:  2.40nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151733((3S,4R)-4-[4-(2-Chloro-benzyloxy)-benzenesulfonyl]...)
Affinity DataIC50:  2.70nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151740((3S,4R)-3-Hydroxy-4-(4''-methyl-biphenyl-4-sulfony...)
Affinity DataIC50: <3nMAssay Description:Inhibitory concentration against matrix metalloprotease 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151744((3S,4R)-3-Hydroxy-4-[4-(3-methyl-benzyloxy)-benzen...)
Affinity DataIC50:  5nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151732(4-[4-(2,4-Dichloro-benzyloxy)-benzenesulfonyl]-3-h...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of matrix metalloprotease 9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50151732(4-[4-(2,4-Dichloro-benzyloxy)-benzenesulfonyl]-3-h...)
Affinity DataIC50:  8.10nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151731(3-Hydroxy-4-(4-o-tolyloxy-benzenesulfonyl)-tetrahy...)
Affinity DataIC50:  9.80nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151732(4-[4-(2,4-Dichloro-benzyloxy)-benzenesulfonyl]-3-h...)
Affinity DataIC50:  12nMAssay Description:Inhibition of matrix metalloprotease 2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50113022((2R,4S)-1-[4-(2-Chloro-benzyloxy)-benzenesulfonyl]...)
Affinity DataIC50:  12nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151747((3S,4R)-4-[4-(2,5-Dichloro-benzyloxy)-benzenesulfo...)
Affinity DataIC50:  13nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151743((3S,4R)-4-[4-(2,3-Dichloro-benzyloxy)-benzenesulfo...)
Affinity DataIC50:  15nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151735((3S,4R)-4-[4-(2,4-Dimethyl-benzyloxy)-benzenesulfo...)
Affinity DataIC50:  17nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151748(3-Hydroxy-4-[4-(2-methyl-benzyloxy)-benzenesulfony...)
Affinity DataIC50:  21nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50151739(4-[4-(2,5-Dimethyl-benzyloxy)-benzenesulfonyl]-3-h...)
Affinity DataIC50:  26nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151737(3-Hydroxy-4-[4-(2-trifluoromethyl-benzyloxy)-benze...)
Affinity DataIC50:  28nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151751(3-Hydroxy-4-(3''-methyl-biphenyl-4-sulfonyl)-tetra...)
Affinity DataIC50: <30nMAssay Description:Inhibitory concentration against matrix metalloprotease 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151749(4-[4-(2-Chloro-benzyloxy)-benzenesulfonyl]-3-metho...)
Affinity DataIC50:  38nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50151733((3S,4R)-4-[4-(2-Chloro-benzyloxy)-benzenesulfonyl]...)
Affinity DataIC50:  40nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151752((3S,4R)-4-[4-(2,4-Dichloro-benzyloxy)-benzenesulfo...)
Affinity DataIC50:  46nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50151748(3-Hydroxy-4-[4-(2-methyl-benzyloxy)-benzenesulfony...)
Affinity DataIC50:  55nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151732(4-[4-(2,4-Dichloro-benzyloxy)-benzenesulfonyl]-3-h...)
Affinity DataIC50:  55nMAssay Description:Inhibition of matrix metalloprotease 3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50151747((3S,4R)-4-[4-(2,5-Dichloro-benzyloxy)-benzenesulfo...)
Affinity DataIC50:  87nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50151752((3S,4R)-4-[4-(2,4-Dichloro-benzyloxy)-benzenesulfo...)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50151749(4-[4-(2-Chloro-benzyloxy)-benzenesulfonyl]-3-metho...)
Affinity DataIC50:  100nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151736(3-Hydroxy-4-(4-p-tolyloxy-benzenesulfonyl)-tetrahy...)
Affinity DataIC50:  120nMAssay Description:Inhibitory concentration against matrix metalloprotease 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151742((3S,4R)-3-Hydroxy-4-(2''-methyl-biphenyl-4-sulfony...)
Affinity DataIC50:  140nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50151743((3S,4R)-4-[4-(2,3-Dichloro-benzyloxy)-benzenesulfo...)
Affinity DataIC50:  140nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151732(4-[4-(2,4-Dichloro-benzyloxy)-benzenesulfonyl]-3-h...)
Affinity DataIC50:  150nMAssay Description:Inhibition of matrix metalloprotease 14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50151737(3-Hydroxy-4-[4-(2-trifluoromethyl-benzyloxy)-benze...)
Affinity DataIC50:  220nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151741((3S,4R)-3-Hydroxy-4-(4-m-tolyloxy-benzenesulfonyl)...)
Affinity DataIC50:  270nMAssay Description:Inhibitory concentration against matrix metalloprotease 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151750(4-[4-(2,6-Dichloro-benzyloxy)-benzenesulfonyl]-3-h...)
Affinity DataIC50: >300nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151745((3S,4R)-4-[4-(2,6-Dimethyl-benzyloxy)-benzenesulfo...)
Affinity DataIC50: >300nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151739(4-[4-(2,5-Dimethyl-benzyloxy)-benzenesulfonyl]-3-h...)
Affinity DataIC50:  300nMAssay Description:Inhibitory concentration against matrix metalloprotease 13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50151734((3S,4R)-4-[4-(4-Chloro-benzyloxy)-benzenesulfonyl]...)
Affinity DataIC50:  330nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50151735((3S,4R)-4-[4-(2,4-Dimethyl-benzyloxy)-benzenesulfo...)
Affinity DataIC50:  370nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50151732(4-[4-(2,4-Dichloro-benzyloxy)-benzenesulfonyl]-3-h...)
Affinity DataIC50:  920nMAssay Description:Inhibitory concentration against matrix metalloprotease 1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50151742((3S,4R)-3-Hydroxy-4-(2''-methyl-biphenyl-4-sulfony...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50151750(4-[4-(2,6-Dichloro-benzyloxy)-benzenesulfonyl]-3-h...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50151751(3-Hydroxy-4-(3''-methyl-biphenyl-4-sulfonyl)-tetra...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50151744((3S,4R)-3-Hydroxy-4-[4-(3-methyl-benzyloxy)-benzen...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50151731(3-Hydroxy-4-(4-o-tolyloxy-benzenesulfonyl)-tetrahy...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50151738(3-Hydroxy-4-[4-(4-methyl-benzyloxy)-benzenesulfony...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory concentration against aggrecanaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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