Compile Data Set for Download or QSAR
maximum 50k data
Found 55 Enz. Inhib. hit(s) with all data for entry = 50037367
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152808((R)-1,2,3,4-Tetrahydro-isoquinoline-3-carboxylic a...)
Affinity DataKi:  12nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155393(4-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[...)
Affinity DataKi:  14nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155370(CHEMBL186074 | Piperidine-3-carboxylic acid [(R)-1...)
Affinity DataKi:  15nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155390(3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[...)
Affinity DataKi:  21nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155401(CHEMBL363122 | Piperidine-4-carboxylic acid [(R)-1...)
Affinity DataKi:  26nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155374(2-Amino-4-methyl-pentanoic acid [(R)-1-(4-chloro-b...)
Affinity DataKi:  30nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155383(CHEMBL263066 | N-[(R)-1-(4-Chloro-benzyl)-2-oxo-2-...)
Affinity DataKi:  38nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155372(CHEMBL186737 | N-[(R)-1-(4-Chloro-benzyl)-2-oxo-2-...)
Affinity DataKi:  40nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155375(CHEMBL364215 | N-[(R)-1-(4-Chloro-benzyl)-2-oxo-2-...)
Affinity DataKi:  41nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155380(-(2R)-[2-aminoacetamido]-3-(4-chlorophenyl)propion...)
Affinity DataKi:  44nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155397(1-Amino-cyclopropanecarboxylic acid [(R)-1-(4-chlo...)
Affinity DataKi:  46nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155387(Azetidine-2-carboxylic acid [(R)-1-(4-chloro-benzy...)
Affinity DataKi:  48nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155389(CHEMBL187957 | Pyrrolidine-2-carboxylic acid [(R)-...)
Affinity DataKi:  50nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155367(2-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[...)
Affinity DataKi:  66nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155382(4-(2R)-[2-methoxyacetamido]3-(4-chlorophenyl)propi...)
Affinity DataKi:  70nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155368(CHEMBL434345 | Piperidine-2-carboxylic acid [(R)-1...)
Affinity DataKi:  75nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155377(3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-(4-{2-[1-(4-m...)
Affinity DataKi:  86nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155399(3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[...)
Affinity DataKi:  110nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155371(3-Amino-N-[(R)-2-(4-{2-[1-(2-amino-benzylamino)-et...)
Affinity DataKi:  120nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155385(3-Amino-N-{(R)-1-(4-chloro-benzyl)-2-[4-(2-{1-[(fu...)
Affinity DataKi:  140nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155386(3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[...)
Affinity DataKi:  140nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155388(3-Amino-N-[(R)-2-(4-{2-[1-((1R,2R)-2-amino-cyclohe...)
Affinity DataKi:  150nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155406(3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[...)
Affinity DataKi:  210nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155394(3-Amino-N-{(R)-1-(4-chloro-benzyl)-2-[4-(2-{[methy...)
Affinity DataKi:  220nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155381(3-Amino-N-{(R)-1-(4-chloro-benzyl)-2-[4-(2-{1-[2-(...)
Affinity DataKi:  290nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155398(3-Amino-propionic acid 1-(4-chloro-benzyl)-2-oxo-2...)
Affinity DataKi:  290nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155400(2,2,2-Trifluoro-ethanesulfonic acid [(R)-1-(4-chlo...)
Affinity DataKi:  410nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155373(3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[...)
Affinity DataKi:  430nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155392(3-Amino-N-[(R)-2-(4-{2-[1-(2-amino-phenylamino)-et...)
Affinity DataKi:  470nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155384((R)-2-Amino-3-(4-chloro-phenyl)-1-(4-{2-[(2-thioph...)
Affinity DataKi:  600nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155370(CHEMBL186074 | Piperidine-3-carboxylic acid [(R)-1...)
Affinity DataKi:  720nMAssay Description:Binding affinity towards human melanocortin 5 receptor expressed in HEK 293 cells was determined by using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155375(CHEMBL364215 | N-[(R)-1-(4-Chloro-benzyl)-2-oxo-2-...)
Affinity DataKi:  730nMAssay Description:Binding affinity towards human melanocortin 5 receptor expressed in HEK 293 cells was determined by using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155380(-(2R)-[2-aminoacetamido]-3-(4-chlorophenyl)propion...)
Affinity DataKi:  990nMAssay Description:Binding affinity towards human melanocortin 5 receptor expressed in HEK 293 cells was determined by using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155390(3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity towards human melanocortin 3 receptor expressed in HEK 293 cells was determined by using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155393(4-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity towards human melanocortin 5 receptor expressed in HEK 293 cells was determined by using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 5(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155390(3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[...)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity towards human melanocortin 5 receptor expressed in HEK 293 cells was determined by using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155366(3-(4-Chloro-phenyl)-1-(4-{2-[(2-thiophen-2-yl-ethy...)
Affinity DataKi:  1.00E+3nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155396(2-Amino-3-(2-chloro-phenyl)-1-(4-{2-[(2-thiophen-2...)
Affinity DataKi:  1.00E+3nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155393(4-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity towards human melanocortin 1 receptor expressed in HEK 293 cells was determined by using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155390(3-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[...)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity towards human melanocortin 1 receptor expressed in HEK 293 cells was determined by using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155393(4-Amino-N-[(R)-1-(4-chloro-benzyl)-2-oxo-2-(4-{2-[...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity towards human melanocortin 3 receptor expressed in HEK 293 cells was determined by using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155370(CHEMBL186074 | Piperidine-3-carboxylic acid [(R)-1...)
Affinity DataKi:  1.40E+3nMAssay Description:Binding affinity towards human melanocortin 3 receptor expressed in HEK 293 cells was determined by using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155379(2-Amino-2-(4-chloro-phenyl)-1-(4-{2-[(2-thiophen-2...)
Affinity DataKi:  1.80E+3nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155375(CHEMBL364215 | N-[(R)-1-(4-Chloro-benzyl)-2-oxo-2-...)
Affinity DataKi:  1.80E+3nMAssay Description:Binding affinity towards human melanocortin 3 receptor expressed in HEK 293 cells was determined by using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 3(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155380(-(2R)-[2-aminoacetamido]-3-(4-chlorophenyl)propion...)
Affinity DataKi:  1.90E+3nMAssay Description:Binding affinity towards human melanocortin 3 receptor expressed in HEK 293 cells was determined by using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocyte-stimulating hormone receptor(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155370(CHEMBL186074 | Piperidine-3-carboxylic acid [(R)-1...)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity towards human melanocortin 1 receptor expressed in HEK 293 cells was determined by using [125I]NDP-MSH as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155402(2-(4-Chloro-phenyl)-2-methyl-1-(4-{2-[(2-thiophen-...)
Affinity DataKi:  3.80E+3nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155395(2-Amino-3-(4-chloro-phenyl)-1-(4-{2-[(2-thiophen-2...)
Affinity DataKi:  3.90E+3nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155391(3-Amino-3-(4-chloro-phenyl)-1-(4-{2-[(2-thiophen-2...)
Affinity DataKi:  5.40E+3nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanocortin receptor 4(Homo sapiens (Human))
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50155405(2-Aminomethyl-3-(4-chloro-phenyl)-1-(4-{2-[(2-thio...)
Affinity DataKi:  6.40E+3nMAssay Description:Tested for inhibition of binding to MC4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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