Compile Data Set for Download or QSAR
maximum 50k data
Found 32 Enz. Inhib. hit(s) with all data for entry = 50016747
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM17967(CHEMBL411885 | Ketopiperazine-based compound, 16 |...)
Affinity DataIC50:  0.400nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173065((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50:  120nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173069((R)-6-(4-Chloro-3-trifluoromethyl-benzyloxymethyl)...)
Affinity DataIC50:  120nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173076((R)-6-(4-Fluoro-3-trifluoromethyl-benzyloxymethyl)...)
Affinity DataIC50:  140nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173063((R)-6-(3,4-Dichloro-benzyloxymethyl)-1-{4-[3-(2-me...)
Affinity DataIC50:  180nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173067((R)-6-(3,5-Dichloro-benzyloxymethyl)-1-{4-[3-(2-me...)
Affinity DataIC50:  180nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173085((R)-6-(2-Fluoro-benzyloxymethyl)-1-{4-[3-(2-methox...)
Affinity DataIC50:  230nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173074((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50:  230nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173079((R)-6-(3,4-Difluoro-benzyloxymethyl)-1-{4-[3-(2-me...)
Affinity DataIC50:  250nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173078((R)-6-(3-Chloro-4-methyl-benzyloxymethyl)-1-{4-[3-...)
Affinity DataIC50:  260nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173086((R)-6-(4-Fluoro-3-methyl-benzyloxymethyl)-1-{4-[3-...)
Affinity DataIC50:  270nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173089((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50:  270nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173081((R)-6-(2-Fluoro-3-trifluoromethyl-benzyloxymethyl)...)
Affinity DataIC50:  270nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173071((R)-6-(4-Chloro-benzyloxymethyl)-1-{4-[3-(2-methox...)
Affinity DataIC50:  300nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173080((R)-6-(3-Chloro-benzyloxymethyl)-1-{4-[3-(2-methox...)
Affinity DataIC50:  330nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173073((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50:  340nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173066((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50:  370nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173075((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50:  410nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173077((R)-6-(2-Chloro-4-fluoro-benzyloxymethyl)-1-{4-[3-...)
Affinity DataIC50:  410nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173082((R)-6-(4-Fluoro-benzyloxymethyl)-1-{4-[3-(2-methox...)
Affinity DataIC50:  450nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173083((S)-6-(4-Chloro-3-trifluoromethyl-benzyloxymethyl)...)
Affinity DataIC50:  594nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173072((R)-6-(3-Methoxy-benzyloxymethyl)-1-{4-[3-(2-metho...)
Affinity DataIC50:  600nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173060((R)-6-(2-Methoxy-benzyloxymethyl)-1-{4-[3-(2-metho...)
Affinity DataIC50:  900nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173062((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173087((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173061(3-((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phen...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173059((R)-6-(3,5-Difluoro-benzyloxymethyl)-1-{4-[3-(2-me...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173068((R)-6-(4-Methoxy-benzyloxymethyl)-1-{4-[3-(2-metho...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173064((S)-6-(4-Fluoro-benzyloxymethyl)-1-{4-[3-(2-methox...)
Affinity DataIC50:  5.59E+3nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173084((R)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50:  6.80E+3nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173070((R)-6-Benzyloxymethyl-1-{4-[3-(2-methoxy-benzyloxy...)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRenin(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50173088((S)-1-{4-[3-(2-Methoxy-benzyloxy)-propoxy]-phenyl}...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibitory activity against renin in fluorescent tGFP assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed