Compile Data Set for Download or QSAR
maximum 50k data
Found 50 Enz. Inhib. hit(s) with all data for entry = 50017891
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187995(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  1nMAssay Description:Inhibition of KDR by cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM8826(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}phenyl)-1...)
Affinity DataIC50:  1nMAssay Description:Inhibition of KDR by cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM8826(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}phenyl)-1...)
Affinity DataIC50:  2nMAssay Description:Inhibition of FLT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM8826(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}phenyl)-1...)
Affinity DataIC50:  3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187997(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50: <3nMAssay Description:Inhibition of FLT4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187997(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187995(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  4nMAssay Description:Inhibition of FLT4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187997(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  5nMAssay Description:Inhibition of KDR by cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188000(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  5nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188000(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  5nMAssay Description:Inhibition of KDR by cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM8826(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}phenyl)-1...)
Affinity DataIC50:  6nMAssay Description:Inhibition of CKITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187996(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  7nMAssay Description:Inhibition of CKITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187996(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  8nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187996(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  10nMAssay Description:Inhibition of FLT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187995(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  11nMAssay Description:Inhibition of CKITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM8826(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}phenyl)-1...)
Affinity DataIC50:  13nMAssay Description:Inhibition of FLT4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187995(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  13nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187992(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  16nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187997(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  18nMAssay Description:Inhibition of CKITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187996(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  19nMAssay Description:Inhibition of TIE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188002(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  19nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187996(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  21nMAssay Description:Inhibition of KDR by cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187992(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  22nMAssay Description:Inhibition of TIE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187992(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  23nMAssay Description:Inhibition of FLT4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187991(1-(4-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)phenyl...)
Affinity DataIC50:  24nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187992(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  28nMAssay Description:Inhibition of CKITMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187997(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  28nMAssay Description:Inhibition of TIE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187997(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  39nMAssay Description:Inhibition of FLT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188002(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  50nMAssay Description:Inhibition of KDR by cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 3(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187996(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  68nMAssay Description:Inhibition of FLT4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188006(1-(4-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)phenyl...)
Affinity DataIC50:  70nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187992(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  75nMAssay Description:Inhibition of FLT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187995(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  79nMAssay Description:Inhibition of FLT1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187993(1-(4-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)phenyl...)
Affinity DataIC50:  97nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187993(1-(4-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)phenyl...)
Affinity DataIC50:  100nMAssay Description:Inhibition of KDR by cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188006(1-(4-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)phenyl...)
Affinity DataIC50:  170nMAssay Description:Inhibition of KDR by cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187998(1-(4-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)phenyl...)
Affinity DataIC50:  225nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187991(1-(4-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)phenyl...)
Affinity DataIC50:  250nMAssay Description:Inhibition of KDR by cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187998(1-(4-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)phenyl...)
Affinity DataIC50:  385nMAssay Description:Inhibition of KDR by cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187995(1-(4-(4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)phen...)
Affinity DataIC50:  415nMAssay Description:Inhibition of TIE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM8826(3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}phenyl)-1...)
Affinity DataIC50:  730nMAssay Description:Inhibition of TIE2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188008(1-(4-((4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)met...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188005(1-(4-((4-aminoisothiazolo[5,4-d]pyrimidin-3-yl)met...)
Affinity DataIC50:  8.60E+3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188007(1-(5-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)furan-...)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188003(1-(5-(4-aminoisoxazolo[5,4-d]pyrimidin-3-yl)furan-...)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187994(3-(4-(5,7-dimethylbenzo[d]oxazol-2-ylamino)phenyl)...)
Affinity DataIC50:  4.30E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188001(3-(4-aminophenyl)isothiazolo[5,4-d]pyrimidin-4-ami...)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188009(3-(4-(5,7-dimethylbenzo[d]oxazol-2-ylamino)phenyl)...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50187999(3-(4-nitrophenyl)isothiazolo[5,4-d]pyrimidin-4-ami...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50188004(CHEMBL211379 | N-(4-(4-aminoisoxazolo[5,4-d]pyrimi...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed