Compile Data Set for Download or QSAR
maximum 50k data
Found 33 Enz. Inhib. hit(s) with all data for entry = 50037908
LigandPNGBDBM25018(3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phe...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataIC50:  3nMAssay Description:Inhibition of p110betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataIC50:  3.60nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataIC50:  10nMAssay Description:Inhibition of PI3Kc2betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25018(3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phe...)
Affinity DataIC50:  16nMAssay Description:Inhibition of p110betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50207163(4-morpholin-4-yl-2-[3-(2-morpholin-4-yl-ethoxy)-ph...)
Affinity DataIC50:  16nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50207172(CHEMBL534951 | [3-(4-morpholin-4-yl-pyrido[3',2':4...)
Affinity DataIC50:  24nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50207169(4-(4-morpholin-4-yl-pyrido[3',2':4,5]furo[3,2-d]py...)
Affinity DataIC50:  26nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50207173(4-morpholin-4-yl-2-[3-(2-thiomorpholin-4-yl-ethoxy...)
Affinity DataIC50:  79nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50207170(2-(3-methoxy-phenyl)-4-morpholin-4-yl-pyrido[3',2'...)
Affinity DataIC50:  100nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50207167(3-(4-morpholin-4-yl-pyrido[3',2':4,5]furo[3,2-d]py...)
Affinity DataIC50:  140nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50207165(4-morpholin-4-yl-2-phenyl-pyrido[3',2':4,5]furo[3,...)
Affinity DataIC50:  160nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50207175(4-morpholin-4-yl-2-[3-(2-piperidin-1-yl-ethoxy)-ph...)
Affinity DataIC50:  170nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM25018(3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phe...)
Affinity DataIC50:  220nMAssay Description:Inhibition of PI3Kc2betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataIC50:  250nMAssay Description:Inhibition of p110gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM12915(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)
Affinity DataIC50:  340nMAssay Description:Inhibition of p110betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50207168(2-(4-morpholin-4-yl-pyrido[3',2':4,5]furo[3,2-d]py...)
Affinity DataIC50:  400nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50207178(4-morpholin-4-yl-pyrido[3',2':4,5]furo[3,2-d]pyrim...)
Affinity DataIC50:  560nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM12915(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)
Affinity DataIC50:  630nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM25018(3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phe...)
Affinity DataIC50:  660nMAssay Description:Inhibition of p110gammaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50207177(4-morpholin-4-yl-pyrido[3',2':4,5]thieno[3,2-d]pyr...)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM12915(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of p110gammaMore data for this Ligand-Target Pair
LigandPNGBDBM50207176(4-morpholin-4-yl-2-phenyl-pyrido[3',2':4,5]thieno[...)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM12915(2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one |...)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of PI3Kc2betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50207174(4-morpholin-4-yl-benzo[4,5]thieno[3,2-d]pyrimidine...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM25018(3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phe...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of Cyclin E/CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50207179(8-morpholin-4-yl-9H-1,5,7,9-tetraaza-fluorene | CH...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50207171(4-morpholin-4-yl-2-phenyl-benzo[4,5]thieno[3,2-d]p...)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of p110alpha by SPA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM25018(3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phe...)
Affinity DataIC50:  9.10E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1/G1/S-specific cyclin-E2(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Cyclin E/CDK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM25045(3-(4-morpholin-4-ylpyrido[2,3]furo[2,4-b]pyrimidin...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM25018(3-(4-morpholin-4-ylthieno[3,2-d]pyrimidin-2-yl)phe...)
Affinity DataIC50:  4.66E+5nMAssay Description:Inhibition of PKCalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed