Compile Data Set for Download or QSAR
maximum 50k data
Found 44 Enz. Inhib. hit(s) with all data for entry = 50038029
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM35847((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)
Affinity DataKi:  0.330nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM35847((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)
Affinity DataKi:  0.790nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213980(4-(2-((R)-2-((S)-3-hydroxyhept-1-enyl)-5-oxopyrrol...)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213978(4-(2-((R)-2-(4-methylocta-1,3-dienyl)-5-oxopyrroli...)
Affinity DataKi:  4nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM35847((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)
Affinity DataKi:  4.90nMAssay Description:Displacement of [3H]PGE2 from human EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM35847((15S)-prostaglandin E2 | (5Z,11alpha,13E,15S)-11,1...)
Affinity DataKi:  9.10nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213977(4-(2-((R)-2-(4-methylhexa-1,3-dienyl)-5-oxopyrroli...)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213981(4-(2-((R)-2-(octa-1,3-dienyl)-5-oxopyrrolidin-1-yl...)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213979(4-(2-((R)-2-(3-methylocta-1,3-dienyl)-5-oxopyrroli...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]PGE2 from human EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213974(4-(2-((R)-2-oxo-5-(4-phenylpenta-1,3-dienyl)pyrrol...)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213976((R)-4-(2-(2-(4-methylpenta-1,3-dienyl)-5-oxopyrrol...)
Affinity DataKi:  45nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213978(4-(2-((R)-2-(4-methylocta-1,3-dienyl)-5-oxopyrroli...)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]PGE2 from human EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213983(4-(2-((R)-2-(4-(cyclopentylmethyl)penta-1,3-dienyl...)
Affinity DataKi:  60nMAssay Description:Displacement of [3H]PGE2 from human EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213981(4-(2-((R)-2-(octa-1,3-dienyl)-5-oxopyrrolidin-1-yl...)
Affinity DataKi:  88nMAssay Description:Displacement of [3H]PGE2 from human EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213983(4-(2-((R)-2-(4-(cyclopentylmethyl)penta-1,3-dienyl...)
Affinity DataKi:  117nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213980(4-(2-((R)-2-((S)-3-hydroxyhept-1-enyl)-5-oxopyrrol...)
Affinity DataKi:  126nMAssay Description:Displacement of [3H]PGE2 from human EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213975(4-(2-((R)-2-(4-methylocta-1,3-dienyl)-5-oxopyrroli...)
Affinity DataKi:  134nMAssay Description:Displacement of [3H]PGE2 from human EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213979(4-(2-((R)-2-(3-methylocta-1,3-dienyl)-5-oxopyrroli...)
Affinity DataKi:  145nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213977(4-(2-((R)-2-(4-methylhexa-1,3-dienyl)-5-oxopyrroli...)
Affinity DataKi:  173nMAssay Description:Displacement of [3H]PGE2 from human EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213975(4-(2-((R)-2-(4-methylocta-1,3-dienyl)-5-oxopyrroli...)
Affinity DataKi:  181nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50411582(CHEMBL2096894)
Affinity DataKi:  443nMAssay Description:Displacement of [3H]PGE2 from human EP4 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213974(4-(2-((R)-2-oxo-5-(4-phenylpenta-1,3-dienyl)pyrrol...)
Affinity DataKi:  749nMAssay Description:Displacement of [3H]PGE2 from human EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50411582(CHEMBL2096894)
Affinity DataKi:  802nMAssay Description:Displacement of [3H]PGE2 from human EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213976((R)-4-(2-(2-(4-methylpenta-1,3-dienyl)-5-oxopyrrol...)
Affinity DataKi:  1.85E+3nMAssay Description:Displacement of [3H]PGE2 from human EP2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213980(4-(2-((R)-2-((S)-3-hydroxyhept-1-enyl)-5-oxopyrrol...)
Affinity DataKi:  9.00E+3nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213980(4-(2-((R)-2-((S)-3-hydroxyhept-1-enyl)-5-oxopyrrol...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213975(4-(2-((R)-2-(4-methylocta-1,3-dienyl)-5-oxopyrroli...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213978(4-(2-((R)-2-(4-methylocta-1,3-dienyl)-5-oxopyrroli...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213975(4-(2-((R)-2-(4-methylocta-1,3-dienyl)-5-oxopyrroli...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]PGE2 from human EP1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213978(4-(2-((R)-2-(4-methylocta-1,3-dienyl)-5-oxopyrroli...)
Affinity DataKi:  1.00E+4nMAssay Description:Displacement of [3H]PGE2 from human EP3 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213981(4-(2-((R)-2-(octa-1,3-dienyl)-5-oxopyrrolidin-1-yl...)
Affinity DataEC50:  197nMAssay Description:Agonist activity at EP2 receptor expressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213979(4-(2-((R)-2-(3-methylocta-1,3-dienyl)-5-oxopyrroli...)
Affinity DataEC50:  23nMAssay Description:Agonist activity at EP2 receptor expressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213978(4-(2-((R)-2-(4-methylocta-1,3-dienyl)-5-oxopyrroli...)
Affinity DataEC50:  0.100nMAssay Description:Agonist activity at EP4 receptor expressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213978(4-(2-((R)-2-(4-methylocta-1,3-dienyl)-5-oxopyrroli...)
Affinity DataEC50:  35nMAssay Description:Agonist activity at EP2 receptor expressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213979(4-(2-((R)-2-(3-methylocta-1,3-dienyl)-5-oxopyrroli...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at EP4 receptor expressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213981(4-(2-((R)-2-(octa-1,3-dienyl)-5-oxopyrrolidin-1-yl...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at EP4 receptor expressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213976((R)-4-(2-(2-(4-methylpenta-1,3-dienyl)-5-oxopyrrol...)
Affinity DataEC50:  4nMAssay Description:Agonist activity at EP4 receptor expressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213980(4-(2-((R)-2-((S)-3-hydroxyhept-1-enyl)-5-oxopyrrol...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at EP2 receptor expressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213975(4-(2-((R)-2-(4-methylocta-1,3-dienyl)-5-oxopyrroli...)
Affinity DataEC50:  222nMAssay Description:Agonist activity at EP2 receptor expressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213980(4-(2-((R)-2-((S)-3-hydroxyhept-1-enyl)-5-oxopyrrol...)
Affinity DataEC50:  0.00200nMAssay Description:Agonist activity at EP4 receptor expressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213975(4-(2-((R)-2-(4-methylocta-1,3-dienyl)-5-oxopyrroli...)
Affinity DataEC50:  15nMAssay Description:Agonist activity at EP4 receptor expressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213977(4-(2-((R)-2-(4-methylhexa-1,3-dienyl)-5-oxopyrroli...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at EP4 receptor expressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213974(4-(2-((R)-2-oxo-5-(4-phenylpenta-1,3-dienyl)pyrrol...)
Affinity DataEC50:  0.5nMAssay Description:Agonist activity at EP4 receptor expressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Emd-Serono Research Institute

Curated by ChEMBL
LigandPNGBDBM50213974(4-(2-((R)-2-oxo-5-(4-phenylpenta-1,3-dienyl)pyrrol...)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at EP2 receptor expressed in HEK293 cells assessed as cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed