Compile Data Set for Download or QSAR
maximum 50k data
Found 8 Enz. Inhib. hit(s) with all data for entry = 50020907
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM21896(4-[(3-chloro-4-fluorophenyl)amino]-6-[(1H-imidazol...)
Affinity DataIC50:  30nMAssay Description:Inhibition of EGFR kinase autophosphorylation in A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50218849(4-cycloheptylamino-6-[(pyridin-3-ylmethyl)-amino]-...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of EGFR kinase autophosphorylation in A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50218849(4-cycloheptylamino-6-[(pyridin-3-ylmethyl)-amino]-...)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of Src kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50218848(4-cyclopentylamino-6-[(pyridin-3-ylmethyl)-amino]-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of EGFR kinase autophosphorylation in A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50218861(4-tert-butylamino-6-[(pyridin-3-ylmethyl)-amino]-[...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of EGFR kinase autophosphorylation in A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50218843(4-cyclohexylamino-6-[(pyridin-3-ylmethyl)-amino]-[...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of EGFR kinase autophosphorylation in A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50218859(4-(1,1-dimethylpropylamino)-6-[(pyridin-3-ylmethyl...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of EGFR kinase autophosphorylation in A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50218847(4-cyclopropylamino-6-[(pyridin-3-ylmethyl)-amino]-...)
Affinity DataIC50: >4.00E+4nMAssay Description:Inhibition of EGFR kinase autophosphorylation in A431 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed