Compile Data Set for Download or QSAR
maximum 50k data
Found 37 Enz. Inhib. hit(s) with all data for entry = 50042265
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50130785(CHEMBL542453 | CHEMBL609978 | {4-[6-(Allyl-methyl-...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128063(Allyl-{6-[3-(4-bromo-phenyl)-benzo[d]isothiazol-6-...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128054(Allyl-{6-[1-(4-bromo-phenyl)-isoquinolin-6-yloxy]-...)
Affinity DataIC50:  3.5nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128055(Allyl-{6-[4-(4-bromo-phenyl)-1H-benzo[d][1,2]oxazi...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50130788(CHEMBL116705 | CHEMBL611484 | {4-[6-(Allyl-methyl-...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50130783(CHEMBL115020 | CHEMBL611485 | {4-[6-(Allyl-methyl-...)
Affinity DataIC50:  4.60nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128050(CHEMBL114259 | CHEMBL416694 | N-allyl-6-(4-(4-brom...)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50130786(CHEMBL115923 | CHEMBL611486 | {4-[6-(Allyl-methyl-...)
Affinity DataIC50:  6.20nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50130774(CHEMBL115375 | CHEMBL611757 | {4-[6-(Allyl-methyl-...)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128065(CHEMBL304858 | CHEMBL324162 | N-allyl-6-(4-(4-brom...)
Affinity DataIC50:  6.5nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50130775(CHEMBL554209 | CHEMBL611758 | {4-[6-(Allyl-methyl-...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50423108(CHEMBL612024)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50130784(Allyl-{6-[1-(4-bromo-phenyl)-3,4-dihydro-isoquinol...)
Affinity DataIC50:  7.90nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50130787(CHEMBL114266 | CHEMBL612025 | {6-[6-(Allyl-methyl-...)
Affinity DataIC50:  8.70nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50130776(Allyl-{6-[4-(4-bromo-phenyl)-2H-chromen-7-yloxy]-h...)
Affinity DataIC50:  11nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50130781(Allyl-{6-[4-(4-bromo-phenyl)-quinazolin-7-yloxy]-h...)
Affinity DataIC50:  12nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128064((E)-N-allyl-4-(3-(4-bromophenyl)benzo[b]thiophen-6...)
Affinity DataIC50:  13nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50130777((4-Bromo-phenyl)-(4-{6-[(3-hydroxy-propyl)-methyl-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128058(ALLYL-{6-[3-(4-BROMO-PHENYL)-1-METHYL-1H-INDAZOL-6...)
Affinity DataIC50:  19nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50423111(CHEMBL611754)
Affinity DataIC50:  19nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128061((4-Bromo-phenyl)-(4-{2-[(cyclopropyl-methyl-amino)...)
Affinity DataIC50:  22nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50130779(CHEMBL553281 | CHEMBL611755 | {4-[6-(Allyl-methyl-...)
Affinity DataIC50:  22nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128067((2E)-N-ALLYL-4-{[3-(4-BROMOPHENYL)-5-FLUORO-1-METH...)
Affinity DataIC50:  29nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128046((E)-N-allyl-4-(3-(4-bromophenyl)benzo[d]isoxazol-6...)
Affinity DataIC50:  29nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50130771((4-Bromo-phenyl)-{4-[6-(cyclopropylmethyl-methyl-a...)
Affinity DataIC50:  32nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50130778((4-Bromo-phenyl)-{4-[6-(cyclopropyl-methyl-amino)-...)
Affinity DataIC50:  35nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128051(Allyl-{6-[3-(4-bromo-phenyl)-1H-indazol-6-yloxy]-h...)
Affinity DataIC50:  39nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128057(CHEMBL262532 | N-(6-(1-(4-fluorobenzoyl)piperidin-...)
Affinity DataIC50:  48nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128059(CHEMBL66359 | N-allyl-6-(1-(4-fluorobenzoyl)piperi...)
Affinity DataIC50:  71nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128048((4-Bromo-phenyl)-{4-[6-(cyclopropyl-methyl-amino)-...)
Affinity DataIC50:  98nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128072((4-{2-[(Allyl-cyclopropyl-amino)-methyl]-cycloprop...)
Affinity DataIC50:  224nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50412870(CHEMBL612028)
Affinity DataIC50:  240nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128069((4-Bromo-phenyl)-(4-{2-[(cyclopropyl-methyl-amino)...)
Affinity DataIC50:  437nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128056((E)-N-allyl-4-(3-(4-bromophenyl)benzofuran-6-yloxy...)
Affinity DataIC50:  501nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128045(ALLYL-{6-[3-(4-BROMO-PHENYL)-BENZOFURAN-6-YLOXY]-H...)
Affinity DataIC50:  617nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128047((E)-N-allyl-4-(4-(6-bromobenzo[d]isothiazol-3-yl)p...)
Affinity DataIC50:  1.86E+3nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLanosterol synthase(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM50128052(Allyl-{6-[4-(6-bromo-benzo[d]isothiazol-3-yl)-phen...)
Affinity DataIC50:  1.91E+3nMAssay Description:Inhibition of oxidosqualene cyclaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed