Compile Data Set for Download or QSAR
maximum 50k data
Found 112 Enz. Inhib. hit(s) with all data for entry = 50022018
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM11551((3R)-N-hydroxy-2-[(4-methoxy-1,1-biphenyl-4-yl)met...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50160855(1-[4-(4-chloro-phenoxy)-phenyl]-1,7,9-triaza-spiro...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50160855(1-[4-(4-chloro-phenoxy)-phenyl]-1,7,9-triaza-spiro...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM11551((3R)-N-hydroxy-2-[(4-methoxy-1,1-biphenyl-4-yl)met...)
Affinity DataKi:  0.900nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50160855(1-[4-(4-chloro-phenoxy)-phenyl]-1,7,9-triaza-spiro...)
Affinity DataKi:  1nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM11551((3R)-N-hydroxy-2-[(4-methoxy-1,1-biphenyl-4-yl)met...)
Affinity DataKi:  1.20nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230525((S)-3-(N-(4-(4-chlorophenoxy)phenyl)methan-2-ylsul...)
Affinity DataIC50:  0.460nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230526((S)-N-hydroxy-2-(isopropylamino)-3-(N-(4-(p-tolylo...)
Affinity DataIC50:  0.520nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230497((S)-N-hydroxy-2-(phenylamino)-3-(N-(4-(p-tolyloxy)...)
Affinity DataIC50:  0.520nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230508((S)-N-hydroxy-2-((S)-1-phenylethylamino)-3-(N-(4-(...)
Affinity DataIC50:  0.540nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230496((S)-N-hydroxy-2-(3-methoxyphenylamino)-3-(N-(4-(p-...)
Affinity DataIC50:  0.620nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230512((S)-2-(cis-2,6-dimethylmorpholino)-N-hydroxy-3-(N-...)
Affinity DataIC50:  0.680nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230507((S)-2-(3-fluorophenylamino)-N-hydroxy-3-(N-(4-(p-t...)
Affinity DataIC50:  0.890nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230518((S)-2-(cis-2,6-dimethylmorpholino)-N-hydroxy-3-(N-...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230516((S)-2-(4-fluorophenylamino)-N-hydroxy-3-(N-(4-(p-t...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230499((S)-N-hydroxy-2-(isobutylamino)-3-(N-(4-(p-tolylox...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230521((S)-N-hydroxy-2-((R)-1-phenylethylamino)-3-(N-(4-(...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230524((S)-2-(cyclopentylamino)-N-hydroxy-3-(N-(4-(p-toly...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230515((S)-2-(1,1-dioxo-1lambda*6*-thiomorpholin-4-yl)-N-...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230505((S)-N-hydroxy-2-(pyridin-4-ylmethylamino)-3-(N-(4-...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230528((S)-N-hydroxy-2-(4-hydroxypiperidin-1-yl)-3-(N-(4-...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230531((S)-N-hydroxy-2-morpholino-3-(N-(4-(p-tolyloxy)phe...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230522((S)-3-(N-(4-(4-chlorophenoxy)phenyl)methan-2-ylsul...)
Affinity DataIC50:  2nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230523((S)-N-hydroxy-2-(piperidin-1-yl)-3-(N-(4-(4-(trifl...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230506((S)-N-hydroxy-2-(isopropylamino)-3-(N-(4-(4-(trifl...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230501((S)-1-(1-(hydroxyamino)-1-oxo-3-(N-(4-(4-(trifluor...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230525((S)-3-(N-(4-(4-chlorophenoxy)phenyl)methan-2-ylsul...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230512((S)-2-(cis-2,6-dimethylmorpholino)-N-hydroxy-3-(N-...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230519((S)-N-hydroxy-2-(pyridin-3-ylmethylamino)-3-(N-(4-...)
Affinity DataIC50:  2.80nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230514((S)-N-hydroxy-2-morpholino-3-(N-(4-(4-(trifluorome...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230498((S)-N-hydroxy-2-(4-(methylsulfonyl)piperazin-1-yl)...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230526((S)-N-hydroxy-2-(isopropylamino)-3-(N-(4-(p-tolylo...)
Affinity DataIC50:  4nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230534((S)-3-(N-(4-(4-chlorophenoxy)phenyl)methan-15-ylsu...)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230515((S)-2-(1,1-dioxo-1lambda*6*-thiomorpholin-4-yl)-N-...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230533((S)-2-(4-acetylpiperazin-1-yl)-N-hydroxy-3-(N-(4-(...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230531((S)-N-hydroxy-2-morpholino-3-(N-(4-(p-tolyloxy)phe...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230510(CHEMBL252022 | N-{(S)-1-hydroxycarbamoyl-2-[methan...)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230501((S)-1-(1-(hydroxyamino)-1-oxo-3-(N-(4-(4-(trifluor...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230522((S)-3-(N-(4-(4-chlorophenoxy)phenyl)methan-2-ylsul...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230518((S)-2-(cis-2,6-dimethylmorpholino)-N-hydroxy-3-(N-...)
Affinity DataIC50:  5.60nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230528((S)-N-hydroxy-2-(4-hydroxypiperidin-1-yl)-3-(N-(4-...)
Affinity DataIC50:  5.70nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230530((S)-2-(benzylamino)-N-hydroxy-3-(N-(4-(p-tolyloxy)...)
Affinity DataIC50:  7.10nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230523((S)-N-hydroxy-2-(piperidin-1-yl)-3-(N-(4-(4-(trifl...)
Affinity DataIC50:  7.60nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230517((S)-N,2-dihydroxy-3-(N-(4-(p-tolyloxy)phenyl)metha...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230533((S)-2-(4-acetylpiperazin-1-yl)-N-hydroxy-3-(N-(4-(...)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230532((S)-N-hydroxy-2-(isopropyl(methyl)amino)-3-(N-(4-(...)
Affinity DataIC50:  8.80nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230506((S)-N-hydroxy-2-(isopropylamino)-3-(N-(4-(4-(trifl...)
Affinity DataIC50:  9.20nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230514((S)-N-hydroxy-2-morpholino-3-(N-(4-(4-(trifluorome...)
Affinity DataIC50:  9.30nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230505((S)-N-hydroxy-2-(pyridin-4-ylmethylamino)-3-(N-(4-...)
Affinity DataIC50:  9.5nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50230498((S)-N-hydroxy-2-(4-(methylsulfonyl)piperazin-1-yl)...)
Affinity DataIC50:  9.90nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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