Compile Data Set for Download or QSAR
maximum 50k data
Found 32 Enz. Inhib. hit(s) with all data for entry = 50025879
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Affinity DataIC50:  0.200nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMelatonin receptor type 1B(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | Melatonin | N-[2-(5-methoxy-1H-indol-3-...)
Affinity DataIC50:  0.530nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetMelatonin receptor type 1A(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50037242(CHEMBL323332 | N-(2-(5-methoxybenzofuran-3-yl)ethy...)
Affinity DataIC50:  0.600nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50037242(CHEMBL323332 | N-(2-(5-methoxybenzofuran-3-yl)ethy...)
Affinity DataIC50:  0.700nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260394(5-MCA-NAT | 5-methoxycarbonylamino-N-acetyltryptam...)
Affinity DataIC50:  100nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260402(CHEMBL505744 | N-(2-(5-Methylcarbamoyl-benzo[b]fur...)
Affinity DataIC50:  189nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260398(CHEMBL494566 | N-(2-(5-Methoxycarbonyl-benzo[b]fur...)
Affinity DataIC50:  389nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260410(CHEMBL493424 | N-(2-(5-Methoxycarbonylamino-benzo[...)
Affinity DataIC50:  560nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260400(CHEMBL522528 | N-(2-(5-Carboxamido-benzo[b]furan-3...)
Affinity DataIC50:  1.00E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260402(CHEMBL505744 | N-(2-(5-Methylcarbamoyl-benzo[b]fur...)
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260404(CHEMBL522674 | N-(2-(5-Methylcarbamoyl-benzo[b]fur...)
Affinity DataIC50:  1.22E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260411(CHEMBL493607 | N-(2-(5-Trifluoroacetamido-benzo[b]...)
Affinity DataIC50:  2.00E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260410(CHEMBL493424 | N-(2-(5-Methoxycarbonylamino-benzo[...)
Affinity DataIC50:  2.69E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260398(CHEMBL494566 | N-(2-(5-Methoxycarbonyl-benzo[b]fur...)
Affinity DataIC50:  3.88E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260394(5-MCA-NAT | 5-methoxycarbonylamino-N-acetyltryptam...)
Affinity DataIC50:  4.00E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260407(CHEMBL521826 | N-(2-(5-Methoxycarbonylamino-benzo[...)
Affinity DataIC50:  4.58E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260408(CHEMBL493414 | N-(2-(5-Methoxycarbonylamino-benzo[...)
Affinity DataIC50:  5.32E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260408(CHEMBL493414 | N-(2-(5-Methoxycarbonylamino-benzo[...)
Affinity DataIC50:  5.32E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260407(CHEMBL521826 | N-(2-(5-Methoxycarbonylamino-benzo[...)
Affinity DataIC50:  5.35E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260395(CHEMBL495232 | N-(2-(5-Methoxycarbonylamino-benzo[...)
Affinity DataIC50:  5.90E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260395(CHEMBL495232 | N-(2-(5-Methoxycarbonylamino-benzo[...)
Affinity DataIC50:  8.18E+3nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260399(CHEMBL494567 | N-(2-(5-Methoxycarbonyl-benzo[b]fur...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260399(CHEMBL494567 | N-(2-(5-Methoxycarbonyl-benzo[b]fur...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260400(CHEMBL522528 | N-(2-(5-Carboxamido-benzo[b]furan-3...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260409(CHEMBL521827 | N-(2-(5-Methoxycarbonylamino-benzo[...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260401(3-(2-(furan-2-carboxamido)ethyl)benzofuran-5-carbo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260411(CHEMBL493607 | N-(2-(5-Trifluoroacetamido-benzo[b]...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1A(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260405(CHEMBL493579 | N-(2-(5-Methylcarbamoyl-benzo[b]fur...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260404(CHEMBL522674 | N-(2-(5-Methylcarbamoyl-benzo[b]fur...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260405(CHEMBL493579 | N-(2-(5-Methylcarbamoyl-benzo[b]fur...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260409(CHEMBL521827 | N-(2-(5-Methoxycarbonylamino-benzo[...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelatonin receptor type 1B(Homo sapiens (Human))
Université

Curated by ChEMBL
LigandPNGBDBM50260401(3-(2-(furan-2-carboxamido)ethyl)benzofuran-5-carbo...)
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed