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Found 22 Enz. Inhib. hit(s) with all data for entry = 50027132
TargetThrombopoietin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50248106(CHEMBL461101 | ELTROMBOPAG | Eltrombopag olamine)
Affinity DataEC50:  38nMAssay Description:Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50265151(3-acetamido-7-(4-butylphenyl)-6-fluoro-5,10-dihydr...)
Affinity DataEC50:  376nMAssay Description:Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50264911(7-(4-butylphenyl)-5,10-dihydroindeno[1,2-b]indole-...)
Affinity DataEC50:  160nMAssay Description:Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50264912(7-(4-butylphenyl)-5,10-dihydroindeno[1,2-b]indole-...)
Affinity DataEC50:  86nMAssay Description:Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50264951(6-fluoro-7-(4-propylphenyl)-5,10-dihydroindeno[1,2...)
Affinity DataEC50:  37nMAssay Description:Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50264952(6-fluoro-7-(4-fluoro-3-methylphenyl)-5,10-dihydroi...)
Affinity DataEC50:  26nMAssay Description:Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50264953(6-fluoro-7-(4-fluoro-3-methylphenyl)-5,10-dihydroi...)
Affinity DataEC50:  277nMAssay Description:Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50264954(7-(4-butylphenyl)-6-fluoro-10,10-dimethyl-5,10-dih...)
Affinity DataEC50:  111nMAssay Description:Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50264987(9-(4-Butyl-phenyl)-5,5-dioxo-6,11-dihydro-5H-5lamb...)
Affinity DataEC50:  449nMAssay Description:Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50264988(10-fluoro-9-(4-fluoro-3-methylphenyl)-6,11-dihydro...)
Affinity DataEC50:  1.43E+3nMAssay Description:Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50264989(11-Fluoro-10-(4-fluoro-3-methyl-phenyl)-7-oxo-5,12...)
Affinity DataEC50: >3.00E+4nMAssay Description:Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50265028(4-(6-(4-butylphenyl)-7-fluoro-1H-indol-2-yl)benzoi...)
Affinity DataEC50:  117nMAssay Description:Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50265029(4-(6-(4-butylphenyl)-7-fluoro-1H-indol-2-yl)benzam...)
Affinity DataEC50:  160nMAssay Description:Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50265030(4-(6-(4-butylphenyl)-7-fluoro-1H-indol-2-yl)-2-hyd...)
Affinity DataEC50:  51nMAssay Description:Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50265031(4-(6-(4-butylphenyl)-7-fluoro-3-methyl-1H-indol-2-...)
Affinity DataEC50:  116nMAssay Description:Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50265065(4-(6-(4-butylphenyl)-3-ethyl-7-fluoro-1H-indol-2-y...)
Affinity DataEC50:  228nMAssay Description:Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50265066(4-(6-(4-butylphenyl)-7-fluoro-3-isopropyl-1H-indol...)
Affinity DataEC50: >1.00E+3nMAssay Description:Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50265067(4-(6-(4-butylphenyl)-1H-benzo[d]imidazol-2-yl)benz...)
Affinity DataEC50:  1.26E+3nMAssay Description:Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50265068(4-(6-(4-butylphenyl)-1H-benzo[d]imidazol-2-yl)-2-h...)
Affinity DataEC50:  179nMAssay Description:Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50265108(CHEMBL498581 | N-(7-(4-butylphenyl)-6-fluoro-5,10-...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50265150(2-(7-(4-butylphenyl)-6-fluoro-5,10-dihydroindeno[1...)
Affinity DataEC50:  21nMAssay Description:Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThrombopoietin receptor(Homo sapiens (Human))
Genomics Institute Of The Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM50263504(9-(4-butylphenyl)-6,11-dihydro-5H-benzo[a]carbazol...)
Affinity DataEC50:  111nMAssay Description:Agonist activity at human thrombopoietin receptor expressed in mouse Ba/F3 cells by kinase activation based reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed