Compile Data Set for Download or QSAR
maximum 50k data
Found 27 Enz. Inhib. hit(s) with all data for entry = 50027313
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275692(CHEMBL528989 | N-(1-(3-methoxypropyl)-5-((phenylam...)
Affinity DataIC50:  3nMAssay Description:Inhibition of ITK (unknown origin) by DELPHIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275651(CHEMBL487357 | N-(5-((cyclohexyl(methyl)amino)meth...)
Affinity DataIC50:  6nMAssay Description:Inhibition of ITK (unknown origin) by DELPHIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM26813(CHEMBL460824 | N-[(2E)-5-[benzene(methyl)amido]-1-...)
Affinity DataIC50:  12nMAssay Description:Inhibition of ITK (unknown origin) by DELPHIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275615(3-cyano-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50:  20nMAssay Description:Inhibition of ITK (unknown origin) by DELPHIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275654(4-cyano-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50:  27nMAssay Description:Inhibition of ITK (unknown origin) by DELPHIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275653(CHEMBL487563 | N-(1-(3-(1H-imidazol-1-yl)propyl)-5...)
Affinity DataIC50:  30nMAssay Description:Inhibition of ITK (unknown origin) by DELPHIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275556(4-cyano-N-(5-(((cyclopentylmethyl)(methyl)amino)me...)
Affinity DataIC50:  34nMAssay Description:Inhibition of ITK (unknown origin) by DELPHIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275618(CHEMBL488170 | N-(5-((cyclohexyl(methyl)amino)meth...)
Affinity DataIC50:  36nMAssay Description:Inhibition of ITK (unknown origin) by DELPHIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275652(CHEMBL487358 | N-(1-(3-amino-3-oxopropyl)-5-((cycl...)
Affinity DataIC50:  41nMAssay Description:Inhibition of ITK (unknown origin) by DELPHIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275554(4-cyano-N-(5-((cyclohexylamino)methyl)-1-(3-methox...)
Affinity DataIC50:  45nMAssay Description:Inhibition of ITK (unknown origin) by DELPHIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275690(CHEMBL488398 | N-(1-(3-(1H-imidazol-1-yl)propyl)-5...)
Affinity DataIC50:  46nMAssay Description:Inhibition of ITK (unknown origin) by DELPHIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275501(4-cyano-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50:  46nMAssay Description:Inhibition of ITK (unknown origin) by DELPHIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275587(4-chloro-N-(5-((cyclohexyl(methyl)amino)methyl)-1-...)
Affinity DataIC50:  46nMAssay Description:Inhibition of ITK (unknown origin) by DELPHIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275617(CHEMBL450635 | N-(5-((cyclohexyl(methyl)amino)meth...)
Affinity DataIC50:  47nMAssay Description:Inhibition of ITK (unknown origin) by DELPHIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275555(4-cyano-N-(1-(3-methoxypropyl)-5-((phenylamino)met...)
Affinity DataIC50:  48nMAssay Description:Inhibition of ITK (unknown origin) by DELPHIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275691(CHEMBL488399 | N-(5-((cyclohexylamino)methyl)-1-(3...)
Affinity DataIC50:  53nMAssay Description:Inhibition of ITK (unknown origin) by DELPHIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275585(4-cyano-N-(1-(3-methoxypropyl)-5-(morpholinomethyl...)
Affinity DataIC50:  69nMAssay Description:Inhibition of ITK (unknown origin) by DELPHIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275584(4-cyano-N-(5-((2-methoxyethylamino)methyl)-1-(3-me...)
Affinity DataIC50:  81nMAssay Description:Inhibition of ITK (unknown origin) by DELPHIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275741(4-cyano-N-(1-(3-methoxypropyl)-5-(((1-methylpiperi...)
Affinity DataIC50:  110nMAssay Description:Inhibition of ITK (unknown origin) by DELPHIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275553(4-cyano-N-(1-(3-methoxypropyl)-5-((methylamino)met...)
Affinity DataIC50:  170nMAssay Description:Inhibition of ITK (unknown origin) by DELPHIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275616(3-bromo-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of ITK (unknown origin) by DELPHIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275586(CHEMBL520565 | N-(5-((cyclohexyl(methyl)amino)meth...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ITK (unknown origin) by DELPHIA assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275501(4-cyano-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50: >1.40E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275501(4-cyano-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50: >1.40E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275501(4-cyano-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50: >1.40E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275501(4-cyano-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50: >1.40E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50275501(4-cyano-N-(5-((cyclohexyl(methyl)amino)methyl)-1-(...)
Affinity DataIC50: >1.40E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed