Compile Data Set for Download or QSAR
maximum 50k data
Found 34 Enz. Inhib. hit(s) with all data for entry = 50030257
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM27973(6-Ethynylthieno[3,2-d]pyrimidine, 8 | N-{3-chloro-...)
Affinity DataIC50:  7nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293255((3R,5S)-5-((4-(3-chloro-4-(3-fluorobenzyloxy)pheny...)
Affinity DataIC50:  11nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM27973(6-Ethynylthieno[3,2-d]pyrimidine, 8 | N-{3-chloro-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293255((3R,5S)-5-((4-(3-chloro-4-(3-fluorobenzyloxy)pheny...)
Affinity DataIC50:  14nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM28512((3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)meth...)
Affinity DataIC50:  20nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM28514((3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)meth...)
Affinity DataIC50:  28nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM28513((3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)meth...)
Affinity DataIC50:  32nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293253((R)-1-(2-((4-(3-chloro-4-(3-fluorobenzyloxy)phenyl...)
Affinity DataIC50:  38nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293257((3R,5S)-5-((4-(3-chloro-4-(3-fluorobenzyloxy)pheny...)
Affinity DataIC50:  40nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM28513((3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)meth...)
Affinity DataIC50:  43nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293261(CHEMBL501705 | N-((3R,5S)-5-((4-(3-chloro-4-(3-flu...)
Affinity DataIC50:  50nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM28512((3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)meth...)
Affinity DataIC50:  50nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293250((S)-N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(py...)
Affinity DataIC50:  54nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293253((R)-1-(2-((4-(3-chloro-4-(3-fluorobenzyloxy)phenyl...)
Affinity DataIC50:  58nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293260(CHEMBL525805 | ethyl (3R,5S)-5-((4-(3-chloro-4-(3-...)
Affinity DataIC50:  60nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293258((3R,5S)-5-((4-(3-chloro-4-(3-fluorobenzyloxy)pheny...)
Affinity DataIC50:  63nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM28489((3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)meth...)
Affinity DataIC50:  65nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM28514((3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)meth...)
Affinity DataIC50:  68nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293260(CHEMBL525805 | ethyl (3R,5S)-5-((4-(3-chloro-4-(3-...)
Affinity DataIC50:  78nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293257((3R,5S)-5-((4-(3-chloro-4-(3-fluorobenzyloxy)pheny...)
Affinity DataIC50:  81nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM28489((3R,5S)-5-{2-[4-({3-chloro-4-[(3-fluorophenyl)meth...)
Affinity DataIC50:  84nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293261(CHEMBL501705 | N-((3R,5S)-5-((4-(3-chloro-4-(3-flu...)
Affinity DataIC50:  87nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293252((R)-N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-((1...)
Affinity DataIC50:  88nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293258((3R,5S)-5-((4-(3-chloro-4-(3-fluorobenzyloxy)pheny...)
Affinity DataIC50:  90nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293256(CHEMBL497184 | N-(3-chloro-4-(3-fluorobenzyloxy)ph...)
Affinity DataIC50:  98nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293250((S)-N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(py...)
Affinity DataIC50:  109nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293251((R)-N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-((1...)
Affinity DataIC50:  110nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293256(CHEMBL497184 | N-(3-chloro-4-(3-fluorobenzyloxy)ph...)
Affinity DataIC50:  115nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293254((R)-methyl 2-((4-(3-chloro-4-(3-fluorobenzyloxy)ph...)
Affinity DataIC50:  120nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293252((R)-N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-((1...)
Affinity DataIC50:  120nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293251((R)-N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-((1...)
Affinity DataIC50:  130nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293259((3R,5S)-5-((4-(3-chloro-4-(3-fluorobenzyloxy)pheny...)
Affinity DataIC50:  135nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293254((R)-methyl 2-((4-(3-chloro-4-(3-fluorobenzyloxy)ph...)
Affinity DataIC50:  140nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293259((3R,5S)-5-((4-(3-chloro-4-(3-fluorobenzyloxy)pheny...)
Affinity DataIC50:  141nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed