Compile Data Set for Download or QSAR
maximum 50k data
Found 37 Enz. Inhib. hit(s) with all data for entry = 2967
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26455((2R)-2-({6-[(4-cyano-2-fluorophenyl)methoxy]naphth...)
Affinity DataIC50:  8.50E+4nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26454((2R)-2-({6-[(4-cyano-2-methoxyphenyl)methoxy]napht...)
Affinity DataIC50:  1.00E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26453((2R)-2-({6-[(4-cyanophenyl)methoxy]naphthalene-2-}...)
Affinity DataIC50:  1.05E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26456((2R)-2-({7-[(4-cyanophenyl)methoxy]naphthalene-2-}...)
Affinity DataIC50:  1.22E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26452((2R)-2-{[6-(3-phenylpropoxy)naphthalene-2-]sulfona...)
Affinity DataIC50:  1.32E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26445((2R)-2-{[6-(pentyloxy)naphthalene-2-]sulfonamido}p...)
Affinity DataIC50:  1.70E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26446((2R)-2-{[6-(hexyloxy)naphthalene-2-]sulfonamido}pe...)
Affinity DataIC50:  1.76E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26464((2R)-2-[(7-butoxynaphthalene-2-)sulfonamido]pentan...)
Affinity DataIC50:  1.80E+5nMAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26447((2R)-2-{[6-(2-ethoxy-2-oxoethoxy)naphthalene-2-]su...)
Affinity DataIC50:  1.92E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26451((2R)-2-{[6-(benzyloxy)naphthalene-2-]sulfonamido}p...)
Affinity DataIC50:  2.39E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26444((2R)-2-[(6-butoxynaphthalene-2-)sulfonamido]pentan...)
Affinity DataIC50:  2.80E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26443((2R)-2-[(6-propoxynaphthalene-2-)sulfonamido]penta...)
Affinity DataIC50:  3.05E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26450((2R)-2-{[6-(cyclopentyloxy)naphthalene-2-]sulfonam...)
Affinity DataIC50:  4.00E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26442((2R)-2-[(6-methoxynaphthalene-2-)sulfonamido]penta...)
Affinity DataIC50:  5.90E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26448((2R)-2-{[6-(carboxymethoxy)naphthalene-2-]sulfonam...)
Affinity DataIC50:  6.30E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26460((2S)-2-[(6-butoxynaphthalene-2-)sulfonamido]pentan...)
Affinity DataIC50:  7.10E+5nMAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26440((2R)-2-(naphthalene-2-sulfonamido)pentanedioic aci...)
Affinity DataIC50:  8.10E+5nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26449((2R)-2-{[6-(3-carboxypropoxy)naphthalene-2-]sulfon...)
Affinity DataIC50: >1.00E+6nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26466((2R)-2-[(4-butoxynaphthalene-1-)sulfonamido]pentan...)
Affinity DataIC50: >1.00E+6nMAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26465((2R)-2-[(5-butoxynaphthalene-1-)sulfonamido]pentan...)
Affinity DataIC50: >1.00E+6nMAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26463((2R)-2-[(6-butoxynaphthalene-2-)(methyl)sulfonamid...)
Affinity DataIC50: >1.00E+6nMAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26462((2R)-2-{[(6-butoxynaphthalen-2-yl)methyl]amino}pen...)
Affinity DataIC50: >1.00E+6nMAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26461((2R)-2-[(6-butoxynaphthalen-2-yl)formamido]pentane...)
Affinity DataIC50: >1.00E+6nMAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM24035((2R)-2-[(4-phenylbenzene)sulfonamido]pentanedioic ...)
Affinity DataIC50:  1.72E+6nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26457(4-[(6-butoxynaphthalene-2-)sulfonamido]butanoic ac...)
Affinity DataIC50: >2.00E+6nMAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26441((2R)-2-{[(2S)-2-(naphthalene-2-sulfonamido)propane...)
Affinity DataIC50: >2.00E+6nMpH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26459(1,5-dimethyl (2R)-2-[(6-butoxynaphthalene-2-)sulfo...)
Affinity DataIC50: >2.00E+6nMAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26458(2-[(6-butoxynaphthalene-2-)sulfonamido]acetic acid...)
Affinity DataIC50: >2.00E+6nMAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26438((2R)-2-[(4-acetamidobenzene)sulfonamido]pentanedio...)
Affinity DatapH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26439((2R)-2-[(4-methylbenzene)sulfonamido]pentanedioic ...)
Affinity DatapH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26436((2R)-2-{[(2-chloro-4-fluorophenyl)methane]sulfonam...)
Affinity DatapH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26437((2R)-2-(phenylmethane)sulfonamidopentanedioic acid...)
Affinity DatapH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26430((2R)-2-[(2E)-3-phenylprop-2-enamido]pentanedioic a...)
Affinity DatapH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26433((2R)-2-[2-(naphthalen-2-yloxy)acetamido]pentanedio...)
Affinity DatapH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26434((2R)-2-[3-(3-hydroxyphenyl)propanamido]pentanedioi...)
Affinity DatapH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26435((2R)-2-[1-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)...)
Affinity DatapH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetUDP-N-acetylmuramoylalanine--D-glutamate ligase(Escherichia coli (strain K12))
Lek Pharmaceuticals

LigandPNGBDBM26432((2R)-2-[(3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl)...)
Affinity DatapH: 8.6 T: 2°CAssay Description:The compounds were tested for their ability to inhibit the addition of D-[14C]Glu to UMA. The radioactive substrate and product were separated by re...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed