Compile Data Set for Download or QSAR
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Found 18 Enz. Inhib. hit(s) with all data for entry = 50030506
TargetCaspase-3(Homo sapiens (Human))
Osmania University College For Women

Curated by ChEMBL
LigandPNGBDBM10324((S)-1-[(tert-Butoxycarbonyl)methyl]-5-{1-[2-(pheno...)
Affinity DataIC50:  3nMAssay Description:Inhibition of caspase 3 in human SK-N-SH cells assessed as accumulation of fluorogenic 7-amino-4-methyl coumarin by flurometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Osmania University College For Women

Curated by ChEMBL
LigandPNGBDBM10326((S)-1-(4-Pyridinylmethyl)-5-{1-[2-(phenoxymethyl)p...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of caspase 3 in human SK-N-SH cells assessed as accumulation of fluorogenic 7-amino-4-methyl coumarin by flurometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Osmania University College For Women

Curated by ChEMBL
LigandPNGBDBM10321((S)-1-Allyl-5-{1-[2-(phenoxymethyl)pyrrolidinyl]su...)
Affinity DataIC50:  5nMAssay Description:Inhibition of caspase 3 in human SK-N-SH cells assessed as accumulation of fluorogenic 7-amino-4-methyl coumarin by flurometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Osmania University College For Women

Curated by ChEMBL
LigandPNGBDBM10322((S)-1-(Cyclohexylmethyl)-5-{1-[2-(phenoxymethyl)py...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of caspase 3 in human SK-N-SH cells assessed as accumulation of fluorogenic 7-amino-4-methyl coumarin by flurometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Osmania University College For Women

Curated by ChEMBL
LigandPNGBDBM10315((S)-5-{1-[2-(Anilinomethyl)pyrrolidinyl]sulfonyl}i...)
Affinity DataIC50:  31nMAssay Description:Inhibition of caspase 3 in human SK-N-SH cells assessed as accumulation of fluorogenic 7-amino-4-methyl coumarin by flurometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Osmania University College For Women

Curated by ChEMBL
LigandPNGBDBM10318((S)-5-{1-[2-(Phenoxymethyl)pyrrolidinyl]sulfonyl}i...)
Affinity DataIC50:  44nMAssay Description:Inhibition of caspase 3 in human SK-N-SH cells assessed as accumulation of fluorogenic 7-amino-4-methyl coumarin by flurometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Osmania University College For Women

Curated by ChEMBL
LigandPNGBDBM10319((S)-(+)-5-{1-[2-(Thiophenoxymethyl)pyrrolidinyl]su...)
Affinity DataIC50:  44nMAssay Description:Inhibition of caspase 3 in human SK-N-SH cells assessed as accumulation of fluorogenic 7-amino-4-methyl coumarin by flurometric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Osmania University College For Women

Curated by ChEMBL
LigandPNGBDBM10313((S)-5-{1-[(2-tert-Butoxycarbonyl)pyrrolidinyl]sulf...)
Affinity DataIC50:  70nMAssay Description:Inhibition of caspase 3 in human SK-N-SH cells assessed as accumulation of fluorogenic 7-amino-4-methyl coumarin by flurometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Osmania University College For Women

Curated by ChEMBL
LigandPNGBDBM10305((S)-5-[1-(2-Methoxymethyl)pyrrolidinylsulfonyl]isa...)
Affinity DataIC50:  120nMAssay Description:Inhibition of caspase 3 in human SK-N-SH cells assessed as accumulation of fluorogenic 7-amino-4-methyl coumarin by flurometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Osmania University College For Women

Curated by ChEMBL
LigandPNGBDBM10308(5-(azetidine-1-sulfonyl)-2,3-dihydro-1H-indole-2,3...)
Affinity DataIC50:  170nMAssay Description:Inhibition of caspase 3 in human SK-N-SH cells assessed as accumulation of fluorogenic 7-amino-4-methyl coumarin by flurometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Osmania University College For Women

Curated by ChEMBL
LigandPNGBDBM10325((S)-1-(Carboxymethyl)-5-{1-[2-(phenoxymethyl)pyrro...)
Affinity DataIC50:  170nMAssay Description:Inhibition of caspase 3 in human SK-N-SH cells assessed as accumulation of fluorogenic 7-amino-4-methyl coumarin by flurometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Osmania University College For Women

Curated by ChEMBL
LigandPNGBDBM10312((S)-5-{1-[(2-Methoxycarbonyl)pyrrolidinyl]sulfonyl...)
Affinity DataIC50:  170nMAssay Description:Inhibition of caspase 3 in human SK-N-SH cells assessed as accumulation of fluorogenic 7-amino-4-methyl coumarin by flurometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Osmania University College For Women

Curated by ChEMBL
LigandPNGBDBM10314((2S)-1-[(2,3-dioxo-2,3-dihydro-1H-indole-5-)sulfon...)
Affinity DataIC50:  410nMAssay Description:Inhibition of caspase 3 in human SK-N-SH cells assessed as accumulation of fluorogenic 7-amino-4-methyl coumarin by flurometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Osmania University College For Women

Curated by ChEMBL
LigandPNGBDBM10307(5-{1-[(2-Methoxyethyl)methylamino]sulfonyl}isatin ...)
Affinity DataIC50:  910nMAssay Description:Inhibition of caspase 3 in human SK-N-SH cells assessed as accumulation of fluorogenic 7-amino-4-methyl coumarin by flurometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Osmania University College For Women

Curated by ChEMBL
LigandPNGBDBM10311(5-(azepan-1-ylsulfonyl)-1H-indole-2,3-dione | 5-(a...)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of caspase 3 in human SK-N-SH cells assessed as accumulation of fluorogenic 7-amino-4-methyl coumarin by flurometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Osmania University College For Women

Curated by ChEMBL
LigandPNGBDBM10310(5-(piperidine-1-sulfonyl)-2,3-dihydro-1H-indole-2,...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of caspase 3 in human SK-N-SH cells assessed as accumulation of fluorogenic 7-amino-4-methyl coumarin by flurometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Osmania University College For Women

Curated by ChEMBL
LigandPNGBDBM10309(5-(pyrrolidine-1-sulfonyl)-2,3-dihydro-1H-indole-2...)
Affinity DataIC50:  2.80E+3nMAssay Description:Inhibition of caspase 3 in human SK-N-SH cells assessed as accumulation of fluorogenic 7-amino-4-methyl coumarin by flurometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCaspase-3(Homo sapiens (Human))
Osmania University College For Women

Curated by ChEMBL
LigandPNGBDBM50297258(5-(2-((methyl(phenyl)amino)methyl)pyrrolidin-1-yls...)
Affinity DataIC50:  5.50E+3nMAssay Description:Inhibition of caspase 3 in human SK-N-SH cells assessed as accumulation of fluorogenic 7-amino-4-methyl coumarin by flurometric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed