Compile Data Set for Download or QSAR
maximum 50k data
Found 56 Enz. Inhib. hit(s) with all data for entry = 50038979
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50:  0.280nMAssay Description:Inhibition of human PKCtheta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302036(5-(5-((4-ethylpiperazin-1-yl)methyl)benzofuran-2-y...)
Affinity DataIC50:  0.480nMAssay Description:Inhibition of human PKCtheta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302047(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50:  0.670nMAssay Description:Inhibition of human PKCtheta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302045(4-(4-methyl-1H-indol-5-ylamino)-5-(5-(piperidin-1-...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human PKCtheta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302051(5-(5-((cyclohexylamino)methyl)benzofuran-2-yl)-4-(...)
Affinity DataIC50:  1.40nMAssay Description:Inhibition of human PKCtheta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302035(5-(5-((2,3-dihydroxypropylamino)methyl)benzofuran-...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human PKCtheta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302033(5-(5-((2-hydroxyethylamino)methyl)benzofuran-2-yl)...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human PKCtheta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302043(5-(benzofuran-2-yl)-4-(4-methyl-1H-indol-5-ylamino...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of human PKCtheta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302034(5-(5-((3-hydroxypropylamino)methyl)benzofuran-2-yl...)
Affinity DataIC50:  2.30nMAssay Description:Inhibition of human PKCtheta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302037(5-(5-((4-(2-(dimethylamino)ethyl)piperazin-1-yl)me...)
Affinity DataIC50:  2.40nMAssay Description:Inhibition of human PKCtheta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C epsilon type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of PKCepsilon by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302046(4-(4-methyl-1H-indol-5-ylamino)-5-(5-(piperidin-1-...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human PKCtheta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302049(4-(4-methyl-1H-indol-5-ylamino)-5-(5-(pyrrolidin-1...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human PKCtheta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302040(4-(4-methyl-1H-indol-5-ylamino)-5-(5-(piperazin-1-...)
Affinity DataIC50:  4.30nMAssay Description:Inhibition of PKCdelta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302046(4-(4-methyl-1H-indol-5-ylamino)-5-(5-(piperidin-1-...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of PKCdelta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302040(4-(4-methyl-1H-indol-5-ylamino)-5-(5-(piperazin-1-...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of human PKCtheta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302041(5-(5-((4-methoxypiperazin-1-yl)methyl)benzofuran-2...)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of human PKCtheta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302048(5-(5-((dimethylamino)methyl)benzofuran-2-yl)-4-(4-...)
Affinity DataIC50:  6.40nMAssay Description:Inhibition of human PKCtheta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302047(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50:  9.90nMAssay Description:Inhibition of PKCdelta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302051(5-(5-((cyclohexylamino)methyl)benzofuran-2-yl)-4-(...)
Affinity DataIC50:  10nMAssay Description:Inhibition of PKCdelta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302039(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-(pyridin-...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human PKCtheta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302050(4-(4-methyl-1H-indol-5-ylamino)-5-(5-(morpholinome...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human PKCtheta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302033(5-(5-((2-hydroxyethylamino)methyl)benzofuran-2-yl)...)
Affinity DataIC50:  13nMAssay Description:Inhibition of PKCdelta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302038(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-(methylsu...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human PKCtheta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302036(5-(5-((4-ethylpiperazin-1-yl)methyl)benzofuran-2-y...)
Affinity DataIC50:  16nMAssay Description:Inhibition of PKCdelta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302035(5-(5-((2,3-dihydroxypropylamino)methyl)benzofuran-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of PKCdelta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302040(4-(4-methyl-1H-indol-5-ylamino)-5-(5-(piperazin-1-...)
Affinity DataIC50:  16nMAssay Description:Inhibition of PKCtheta in C57BL/6 mouse T cells assessed as inhibition of anti-CD3 and anti-CD28-induced IL2 production after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50:  17nMAssay Description:Inhibition of PKCdelta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302037(5-(5-((4-(2-(dimethylamino)ethyl)piperazin-1-yl)me...)
Affinity DataIC50:  20nMAssay Description:Inhibition of PKCdelta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50:  21nMAssay Description:Inhibition of PKCtheta in C57BL/6 mouse T cells assessed as inhibition of anti-CD3 and anti-CD28-induced IL2 production after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302034(5-(5-((3-hydroxypropylamino)methyl)benzofuran-2-yl...)
Affinity DataIC50:  21nMAssay Description:Inhibition of PKCdelta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302044(5-(benzo[b]thiophen-2-yl)-4-(4-methyl-1H-indol-5-y...)
Affinity DataIC50:  23nMAssay Description:Inhibition of human PKCtheta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302045(4-(4-methyl-1H-indol-5-ylamino)-5-(5-(piperidin-1-...)
Affinity DataIC50:  25nMAssay Description:Inhibition of PKCdelta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C eta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50:  33nMAssay Description:Inhibition of PKCeta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302049(4-(4-methyl-1H-indol-5-ylamino)-5-(5-(pyrrolidin-1...)
Affinity DataIC50:  43nMAssay Description:Inhibition of PKCdelta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302048(5-(5-((dimethylamino)methyl)benzofuran-2-yl)-4-(4-...)
Affinity DataIC50:  44nMAssay Description:Inhibition of PKCdelta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302043(5-(benzofuran-2-yl)-4-(4-methyl-1H-indol-5-ylamino...)
Affinity DataIC50:  57nMAssay Description:Inhibition of PKCdelta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302041(5-(5-((4-methoxypiperazin-1-yl)methyl)benzofuran-2...)
Affinity DataIC50:  110nMAssay Description:Inhibition of PKCdelta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302050(4-(4-methyl-1H-indol-5-ylamino)-5-(5-(morpholinome...)
Affinity DataIC50:  121nMAssay Description:Inhibition of PKCdelta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302038(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-(methylsu...)
Affinity DataIC50:  138nMAssay Description:Inhibition of PKCdelta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302039(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-(pyridin-...)
Affinity DataIC50:  149nMAssay Description:Inhibition of PKCdelta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C delta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302044(5-(benzo[b]thiophen-2-yl)-4-(4-methyl-1H-indol-5-y...)
Affinity DataIC50:  154nMAssay Description:Inhibition of PKCdelta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50:  260nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C theta type(Mus musculus)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302041(5-(5-((4-methoxypiperazin-1-yl)methyl)benzofuran-2...)
Affinity DataIC50:  360nMAssay Description:Inhibition of PKCtheta in C57BL/6 mouse T cells assessed as inhibition of anti-CD3 and anti-CD28-induced IL2 production after 20 to 24 hrs by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lyn(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50:  730nMAssay Description:Inhibition of LynMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C beta type(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50:  800nMAssay Description:Inhibition of PKCbeta by IMAP fluorescence polarization technologyMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRho-associated protein kinase 1(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibition of ROCK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMAP kinase-activated protein kinase 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibition of MK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50302042(4-(4-methyl-1H-indol-5-ylamino)-5-(5-((4-methylpip...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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