Compile Data Set for Download or QSAR
maximum 50k data
Found 9 Enz. Inhib. hit(s) with all data for entry = 50031085
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50306692(2-(Benzylaminocarbonyloxy)-5-O-benzyl-1,4:3,6-dian...)
Affinity DataIC50:  52nMAssay Description:Inhibition of human plasma BuChE preincubated for 30 mins before substrate addition by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50306693(2-(Benzylaminocarbonyloxy)-5-O-(phenylpropyloxy)-1...)
Affinity DataIC50:  201nMAssay Description:Inhibition of human plasma BuChE preincubated for 30 mins before substrate addition by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50306689(CHEMBL600013 | Isosorbide-di-(benzylcarbamate))
Affinity DataIC50:  400nMAssay Description:Inhibition of human plasma BuChE preincubated for 30 mins before substrate addition by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50306688(CHEMBL606050 | Isosorbide-di-(butylcarbamate))
Affinity DataIC50:  1.22E+3nMAssay Description:Inhibition of human plasma BuChE preincubated for 30 mins before substrate addition by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50306691(2-(Benzylaminocarbonyloxy)-5-deoxy, 5-dehydro-((et...)
Affinity DataIC50:  4.80E+3nMAssay Description:Inhibition of human plasma BuChE preincubated for 30 mins before substrate addition by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50306695(CHEMBL603100 | Isosorbide-di-(4-nitrophenyl carbam...)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of electric eel AChE preincubated for 30 mins before substrate addition by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50306694(CHEMBL600621 | Isosorbide-di-(ethylcarbamate))
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of electric eel AChE preincubated for 30 mins before substrate addition by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50306690(2-(Benzylaminocarbonyloxy)-5-deoxy-L-xylohex-6-eni...)
Affinity DataIC50:  1.03E+4nMAssay Description:Inhibition of human plasma BuChE preincubated for 30 mins before substrate addition by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Trinity College

Curated by ChEMBL
LigandPNGBDBM50306687(CHEMBL600622 | Isosorbide-di-(propylcarbamate))
Affinity DataIC50:  1.04E+4nMAssay Description:Inhibition of human plasma BuChE preincubated for 30 mins before substrate addition by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed