Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with all data for entry = 50031454
TargetHistamine H1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50313618(1-(3-chlorophenyl)-3-(piperidin-2-ylmethyl)imidazo...)
Affinity DataKi:  2.00E+3nMAssay Description:Activity at histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistamine H1 receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50313619(2-((3-phenylimidazolidin-1-yl)methyl)piperidine | ...)
Affinity DataKi:  2.51E+3nMAssay Description:Activity at histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50313618(1-(3-chlorophenyl)-3-(piperidin-2-ylmethyl)imidazo...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human recombinant CYP2D6 by spectrafluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50313618(1-(3-chlorophenyl)-3-(piperidin-2-ylmethyl)imidazo...)
Affinity DataIC50:  7.94E+3nMAssay Description:Displacement of [3H]dofetilide from human ERG by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50313619(2-((3-phenylimidazolidin-1-yl)methyl)piperidine | ...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant CYP2D6 by spectrafluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50313619(2-((3-phenylimidazolidin-1-yl)methyl)piperidine | ...)
Affinity DataIC50:  1.58E+4nMAssay Description:Displacement of [3H]dofetilide from human ERG by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed