Compile Data Set for Download or QSAR
maximum 50k data
Found 9 Enz. Inhib. hit(s) with all data for entry = 50032295
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50326793((+/-)(1S,2S,3R)-2-[(S)-Amino(carboxy)methyl]-3-cyc...)
Affinity DataIC50:  6.20E+4nMAssay Description:Antagonist activity at mGlu2 receptor expressed in CHO cells assessed as increase of cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50326793((+/-)(1S,2S,3R)-2-[(S)-Amino(carboxy)methyl]-3-cyc...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu1 receptor expressed in CHO cells assessed as myo-[2-3H]Inositol turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50138781((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-methyl-c...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu1 receptor expressed in CHO cells assessed as myo-[2-3H]Inositol turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50326793((+/-)(1S,2S,3R)-2-[(S)-Amino(carboxy)methyl]-3-cyc...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu4 receptor expressed in CHO cells assessed as inhibition of forskolin-induced increase of cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50326794((+/-)(1R,2S,3S)-3-[(S)-amino(carboxy)-methyl]-1,10...)
Affinity DataEC50: >50nMAssay Description:Agonist activity at mGlu2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced increase of cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50138781((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-methyl-c...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu4 receptor expressed in CHO cells assessed as inhibition of forskolin-induced increase of cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50326794((+/-)(1R,2S,3S)-3-[(S)-amino(carboxy)-methyl]-1,10...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu4 receptor expressed in CHO cells assessed as inhibition of forskolin-induced increase of cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50326794((+/-)(1R,2S,3S)-3-[(S)-amino(carboxy)-methyl]-1,10...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at mGlu1 receptor expressed in CHO cells assessed as myo-[2-3H]Inositol turnover by scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
The University Of Adelaide

Curated by ChEMBL
LigandPNGBDBM50138781((1S,2S,3R)-2-((S)-Amino-carboxy-methyl)-3-methyl-c...)
Affinity DataEC50: >10nMAssay Description:Agonist activity at mGlu2 receptor expressed in CHO cells assessed as inhibition of forskolin-induced increase of cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed