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Found 12 Enz. Inhib. hit(s) with all data for entry = 50033017
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338198(3-(2-morpholino-7-(pyridin-4-yl)-6,7-dihydro-5H-py...)
Affinity DataIC50:  8.60nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338199(5-(2-Morpholin-4-yl-7-pyridin-3-yl-6,7-dihydro-5H-...)
Affinity DataIC50:  33nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50:  36nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338200(3-(2-morpholino-7-(pyridin-3-yl)-6,7-dihydro-5H-py...)
Affinity DataIC50:  41nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338196(3-(7-(1H-benzo[d]imidazol-6-yl)-2-morpholino-6,7-d...)
Affinity DataIC50:  77nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50:  120nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase mTOR(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of PI3KC2betaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of PI3KC2alphaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Homo sapiens (Human))
Chugai Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50338197(5-(7-(methylsulfonyl)-2-morpholino-6,7-dihydro-5H-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Vps34More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed