BindingDB PrimarySearch_ki

Found 32 Enz. Inhib. hit(s) with all data for entry = 50040841

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)

Ki: 74nMAssay Description:Displacement of [3H]rosiglitazone from N-terminal His-tagged human PPARgamma ligand binding domain expressed in Escherichia coli BL21 DE3 cells by sc...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

ChEBI
CHEMBL PC cid PC sid PDB Patents Similars

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3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM28762((2R)-2-(4-{2-[1,3-benzoxazol-2-yl(heptyl)amino]eth...)

Ki: 88nMAssay Description:Displacement of [3H]rosiglitazone from N-terminal His-tagged human PPARgamma ligand binding domain expressed in Escherichia coli BL21 DE3 cells by sc...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM28763((2S)-2-(4-{2-[1,3-benzoxazol-2-yl(heptyl)amino]eth...)

Ki: 971nMAssay Description:Displacement of [3H]rosiglitazone from N-terminal His-tagged human PPARgamma ligand binding domain expressed in Escherichia coli BL21 DE3 cells by sc...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
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PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM50401010(CHEMBL2206304)

EC50: 800nMAssay Description:Agonist activity at human GAL4-fused PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM50401011(CHEMBL2206303)

EC50: 2.30E+3nMAssay Description:Agonist activity at human GAL4-fused PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM50401012(CHEMBL2206302)

EC50: 150nMAssay Description:Agonist activity at human GAL4-fused PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM50401013(CHEMBL477312)

EC50: 110nMAssay Description:Agonist activity at human GAL4-fused PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL MMDB PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM28763((2S)-2-(4-{2-[1,3-benzoxazol-2-yl(heptyl)amino]eth...)

EC50: 590nMAssay Description:Agonist activity at human GAL4-fused PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM28762((2R)-2-(4-{2-[1,3-benzoxazol-2-yl(heptyl)amino]eth...)

EC50: 70nMAssay Description:Agonist activity at human GAL4-fused PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

MMDB PC cid PC sid PDB Similars

Details Article PubMed MMDB
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM24566(2-({4-chloro-6-[(2,3-dimethylphenyl)amino]pyrimidi...)

EC50: 1.60E+3nMAssay Description:Agonist activity at human GAL4-fused PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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3D Structure (crystal)

Peroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM50401009(CHEMBL2206305)

EC50: 1.72E+3nMAssay Description:Agonist activity at human GAL4-fused PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM50401010(CHEMBL2206304)

EC50: 122nMAssay Description:Agonist activity at human GAL4-fused PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM50401011(CHEMBL2206303)

EC50: 620nMAssay Description:Agonist activity at human GAL4-fused PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM50401012(CHEMBL2206302)

EC50: 25nMAssay Description:Agonist activity at human GAL4-fused PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM50401013(CHEMBL477312)

EC50: 30nMAssay Description:Agonist activity at human GAL4-fused PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL MMDB PC cid PC sid PDB Similars

Details Article PubMed

Peroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM28763((2S)-2-(4-{2-[1,3-benzoxazol-2-yl(heptyl)amino]eth...)

EC50: 56nMAssay Description:Agonist activity at human GAL4-fused PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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Peroxisome proliferator-activated receptor alpha(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM28762((2R)-2-(4-{2-[1,3-benzoxazol-2-yl(heptyl)amino]eth...)

EC50: 3nMAssay Description:Agonist activity at human GAL4-fused PPARalpha ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

MMDB PC cid PC sid PDB Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)

Kd: 120nMAssay Description:Binding affinity to PPARgamma ligand binding domain by isothermal titration calorimetryMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

ChEBI
CHEMBL PC cid PC sid PDB Patents Similars

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3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM50401010(CHEMBL2206304)

Kd: 7.70E+3nMAssay Description:Binding affinity to PPARgamma ligand binding domain by isothermal titration calorimetryMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM50401011(CHEMBL2206303)

Kd: 3.30E+3nMAssay Description:Binding affinity to PPARgamma ligand binding domain by isothermal titration calorimetryMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM50401012(CHEMBL2206302)

Kd: 1.50E+3nMAssay Description:Binding affinity to PPARgamma ligand binding domain by isothermal titration calorimetryMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM50401013(CHEMBL477312)

Kd: 4.50E+3nMAssay Description:Binding affinity to PPARgamma ligand binding domain by isothermal titration calorimetryMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL MMDB PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM28763((2S)-2-(4-{2-[1,3-benzoxazol-2-yl(heptyl)amino]eth...)

Kd: 2.00E+3nMAssay Description:Binding affinity to PPARgamma ligand binding domain by isothermal titration calorimetryMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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Details Article PubMed MMDB
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM28762((2R)-2-(4-{2-[1,3-benzoxazol-2-yl(heptyl)amino]eth...)

Kd: 270nMAssay Description:Binding affinity to PPARgamma ligand binding domain by isothermal titration calorimetryMore data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

MMDB PC cid PC sid PDB Similars

Details Article PubMed MMDB
PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM50085041(2-(4-(3-(4-acetyl-3-hydroxy-2-propylphenoxy)propox...)

EC50: 21nMAssay Description:Agonist activity at human GAL4-fused PPARdelta ligand binding domain expressed in COS-1 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

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3D Structure (crystal)

Peroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM50401010(CHEMBL2206304)

EC50: 570nMAssay Description:Agonist activity at human GAL4-fused PPARdelta ligand binding domain expressed in COS-1 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM50401011(CHEMBL2206303)

EC50: 850nMAssay Description:Agonist activity at human GAL4-fused PPARdelta ligand binding domain expressed in COS-1 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM50401012(CHEMBL2206302)

EC50: 130nMAssay Description:Agonist activity at human GAL4-fused PPARdelta ligand binding domain expressed in COS-1 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM50401009(CHEMBL2206305)

EC50: 2.70E+3nMAssay Description:Agonist activity at human GAL4-fused PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Peroxisome proliferator-activated receptor delta(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM50401013(CHEMBL477312)

EC50: 90nMAssay Description:Agonist activity at human GAL4-fused PPARdelta ligand binding domain expressed in COS-1 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair

PDB Reactome pathway
UniProtKB/SwissProt
antibodypedia GoogleScholar

CHEMBL MMDB PC cid PC sid PDB Similars

Details Article PubMed

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM28681(5-[(4-{2-[methyl(pyridin-2-yl)amino]ethoxy}phenyl)...)

EC50: 20nMAssay Description:Agonist activity at human GAL4-fused PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

ChEBI
CHEMBL PC cid PC sid PDB Patents Similars

Details Article PubMed PDB

3D Structure (crystal)

Peroxisome proliferator-activated receptor gamma(Homo sapiens (Human))
Istituto Tumori&Quot;Giovanni Paolo Ii&Quot

Curated by ChEMBL

PNG

BDBM50401008(CHEMBL2206306)

EC50: 1.70E+3nMAssay Description:Agonist activity at human GAL4-fused PPARgamma ligand binding domain expressed in HepG2 cells after 20 hrs by luciferase reporter gene transactivatio...More data for this Ligand-Target Pair

PDB MMDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed