Compile Data Set for Download or QSAR
maximum 50k data
Found 46 Enz. Inhib. hit(s) with all data for entry = 50042650
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataKi:  8nMAssay Description:Inhibition of human recombinant MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataKi:  20nMAssay Description:Inhibition of human recombinant MMP2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataKi:  33nMAssay Description:Inhibition of human recombinant MMP1More data for this Ligand-Target Pair
TargetStromelysin-1(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM8465((2R)-N-hydroxy-2-[(4-methoxybenzene)(pyridin-3-ylm...)
Affinity DataKi:  43nMAssay Description:Inhibition of human recombinant MMP3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM12074((2R)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...)
Affinity DataIC50:  0.00400nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM12074((2R)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...)
Affinity DataIC50:  0.00700nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM12074((2R)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...)
Affinity DataIC50:  0.00800nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM24025((2R)-3-methyl-2-[(4-phenylbenzene)sulfonamido]buta...)
Affinity DataIC50:  0.0380nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM24025((2R)-3-methyl-2-[(4-phenylbenzene)sulfonamido]buta...)
Affinity DataIC50:  0.0400nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50137279(6-Hydroxy-2-(4-nitro-benzenesulfonyl)-1,2,3,4-tetr...)
Affinity DataIC50:  0.0410nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM24025((2R)-3-methyl-2-[(4-phenylbenzene)sulfonamido]buta...)
Affinity DataIC50:  0.0620nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50137279(6-Hydroxy-2-(4-nitro-benzenesulfonyl)-1,2,3,4-tetr...)
Affinity DataIC50:  0.0760nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50137279(6-Hydroxy-2-(4-nitro-benzenesulfonyl)-1,2,3,4-tetr...)
Affinity DataIC50:  0.25nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50148201(1-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-cycl...)
Affinity DataIC50:  0.650nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50148231(2-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-N-hy...)
Affinity DataIC50:  0.700nMAssay Description:Inhibition of human recombinant MMP2 using (7-amino-4-methyl-coumarin)-Pro-Leu-Gly-Leu-(dinitrophenylamine)-Ala-Arg- NH2 as substrate by fluorimetric...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50106136(2-{[4-(4-Chloro-phenoxy)-benzenesulfonyl]-methyl-a...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage metalloelastase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50428828(CHEMBL2337131)
Affinity DataIC50:  0.930nMAssay Description:Inhibition of MMP12 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50095222(CHEMBL83209 | N-Hydroxy-2-[4-(4-trifluoromethyl-ph...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM24043((2R)-2-({4-[4-(1-benzofuran-2-amido)phenyl]benzene...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50095218(CHEMBL310008 | N-Hydroxy-2-[4-(4-trifluoromethoxy-...)
Affinity DataIC50:  2nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)
Affinity DataIC50:  3nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50428829(CHEMBL2337130)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM12075((2S)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...)
Affinity DataIC50:  8nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)
Affinity DataIC50:  12nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50428829(CHEMBL2337130)
Affinity DataIC50:  12nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM12075((2S)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...)
Affinity DataIC50:  12nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50148231(2-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-N-hy...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human recombinant MMP9 using (7-amino-4-methyl-coumarin)-Pro-Leu-Gly-Leu-(dinitrophenylamine)-Ala-Arg- NH2 as substrate by fluorimetric...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)
Affinity DataIC50:  13nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50096477(3-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-hyd...)
Affinity DataIC50:  15nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50095222(CHEMBL83209 | N-Hydroxy-2-[4-(4-trifluoromethyl-ph...)
Affinity DataIC50:  28nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50095218(CHEMBL310008 | N-Hydroxy-2-[4-(4-trifluoromethoxy-...)
Affinity DataIC50:  33nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)
Affinity DataIC50:  34nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50096477(3-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-hyd...)
Affinity DataIC50:  47nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM12075((2S)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...)
Affinity DataIC50:  47nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50096476((R)-2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-c...)
Affinity DataIC50:  174nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50096476((R)-2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-c...)
Affinity DataIC50:  181nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)
Affinity DataIC50:  200nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50096476((R)-2-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-c...)
Affinity DataIC50:  233nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50096480(4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-5-bro...)
Affinity DataIC50:  236nMAssay Description:Inhibition of MMP9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM12075((2S)-2-{[4-(4-bromophenyl)benzene]sulfonamido}-3-m...)
Affinity DataIC50:  240nMAssay Description:Inhibition of MMP14 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50096480(4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-5-bro...)
Affinity DataIC50:  427nMAssay Description:Inhibition of MMP13 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50096480(4-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-5-bro...)
Affinity DataIC50:  639nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50096477(3-[Benzyl-(4-methoxy-benzenesulfonyl)-amino]-N-hyd...)
Affinity DataIC50:  1.23E+3nMAssay Description:Inhibition of MMP1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50204371(2-{isopropoxy[(4-methoxyphenyl)sulfonyl]amino}-N-h...)
Affinity DataIC50:  3.60E+3nMAssay Description:Inhibition of MMP2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM50161331(2-[(Biphenyl-4-sulfonyl)-isopropoxy-amino]-N-hydro...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Indian Institute Of Technology (Bhu)

Curated by ChEMBL
LigandPNGBDBM13080(CGS 27023A Analog 3 | N-hydroxy-2-[(4-methoxybenze...)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of MMP3 (unknown origin)More data for this Ligand-Target Pair