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Found 13 Enz. Inhib. hit(s) with all data for entry = 50042601
TargetBeta-secretase 2(Rattus norvegicus)
Temple University

Curated by ChEMBL
LigandPNGBDBM50428341(CHEMBL2331713)
Affinity DataIC50:  1nMAssay Description:Inhibition of BACE2-mediated TMEM27 cleavage in rat INS-1E cells expressing doxycycline-dependent human full-length TMEM27 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Rattus norvegicus)
Temple University

Curated by ChEMBL
LigandPNGBDBM50428342(CHEMBL2331710)
Affinity DataIC50:  2nMAssay Description:Inhibition of BACE2-mediated TMEM27 cleavage in rat INS-1E cells expressing doxycycline-dependent human full-length TMEM27 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Rattus norvegicus)
Temple University

Curated by ChEMBL
LigandPNGBDBM50428340(CHEMBL2331712)
Affinity DataIC50:  2nMAssay Description:Inhibition of BACE2-mediated TMEM27 cleavage in rat INS-1E cells expressing doxycycline-dependent human full-length TMEM27 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Rattus norvegicus)
Temple University

Curated by ChEMBL
LigandPNGBDBM50428343(CHEMBL2331708)
Affinity DataIC50:  2nMAssay Description:Inhibition of BACE2-mediated TMEM27 cleavage in rat INS-1E cells expressing doxycycline-dependent human full-length TMEM27 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Rattus norvegicus)
Temple University

Curated by ChEMBL
LigandPNGBDBM50428341(CHEMBL2331713)
Affinity DataIC50:  5nMAssay Description:Inhibition of BACE2-mediated TMEM27 cleavage in rat INS-1E cells expressing doxycycline-dependent human full-length TMEM27 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50428343(CHEMBL2331708)
Affinity DataIC50:  5nMAssay Description:Inhibition of BACE1 in human HEK293 cells transfected with human wild type APP695 assessed as decrease in amyloid beta 40 level after 18 to 20 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Rattus norvegicus)
Temple University

Curated by ChEMBL
LigandPNGBDBM50428339(CHEMBL2331714)
Affinity DataIC50:  11nMAssay Description:Inhibition of BACE2-mediated TMEM27 cleavage in rat INS-1E cells expressing doxycycline-dependent human full-length TMEM27 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50428339(CHEMBL2331714)
Affinity DataIC50:  12nMAssay Description:Inhibition of BACE1 in human HEK293 cells transfected with human wild type APP695 assessed as decrease in amyloid beta 40 level after 18 to 20 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50428340(CHEMBL2331712)
Affinity DataIC50:  26nMAssay Description:Inhibition of BACE1 in human HEK293 cells transfected with human wild type APP695 assessed as decrease in amyloid beta 40 level after 18 to 20 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50428342(CHEMBL2331710)
Affinity DataIC50:  50nMAssay Description:Inhibition of BACE1 in human HEK293 cells transfected with human wild type APP695 assessed as decrease in amyloid beta 40 level after 18 to 20 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50428341(CHEMBL2331713)
Affinity DataIC50:  52nMAssay Description:Inhibition of BACE1 in human HEK293 cells transfected with human wild type APP695 assessed as decrease in amyloid beta 40 level after 18 to 20 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Temple University

Curated by ChEMBL
LigandPNGBDBM50428341(CHEMBL2331713)
Affinity DataIC50:  60nMAssay Description:Inhibition of BACE1 in human HEK293 cells transfected with human wild type APP695 assessed as decrease in amyloid beta 40 level after 18 to 20 hrs by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 2(Rattus norvegicus)
Temple University

Curated by ChEMBL
LigandPNGBDBM50428344(CHEMBL2331711)
Affinity DataIC50:  690nMAssay Description:Inhibition of BACE2-mediated TMEM27 cleavage in rat INS-1E cells expressing doxycycline-dependent human full-length TMEM27 by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed