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Found 21 Enz. Inhib. hit(s) with all data for entry = 50045115
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50025735((5Z,8Z,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic a...)
Affinity DataKi:  87nMAssay Description:Mixed type inhibition of human platelet 12-lipoxygenase assessed as equilibrium inhibitor constant of dissociation from enzyme by measuring 12-HpETE ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50045523(CHEBI:34151 | CHEMBL3310737)
Affinity DataKi:  3.68E+4nMAssay Description:Irreversible inhibition of human reticulocyte 15-lipoxygenase-1 by assessed as equilibrium inhibitor constantMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50025735((5Z,8Z,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic a...)
Affinity DataIC50:  1.00E+3nMAssay Description:Inhibition of human platelet 12-lipoxygenase by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50045523(CHEBI:34151 | CHEMBL3310737)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human reticulocyte 15-lipoxygenase-1 by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50045523(CHEBI:34151 | CHEMBL3310737)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of human platelet 12-lipoxygenase by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50024458(5-oxo-ETE | CHEMBL18028 | ETE-5-Oxo)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of human platelet 12-lipoxygenase by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50024458(5-oxo-ETE | CHEMBL18028 | ETE-5-Oxo)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human reticulocyte 15-lipoxygenase-1 by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Oryctolagus cuniculus (rabbit))
University Of California

Curated by ChEMBL
LigandPNGBDBM50024458(5-oxo-ETE | CHEMBL18028 | ETE-5-Oxo)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of rabbit reticulocyte 15-LOX by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50025735((5Z,8Z,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic a...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of human reticulocyte 15-lipoxygenase-1 by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Oryctolagus cuniculus (rabbit))
University Of California

Curated by ChEMBL
LigandPNGBDBM50025735((5Z,8Z,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic a...)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of rabbit reticulocyte 15-LOX by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50045523(CHEBI:34151 | CHEMBL3310737)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human leukocyte 5-lipoxygenase by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Oryctolagus cuniculus (rabbit))
University Of California

Curated by ChEMBL
LigandPNGBDBM50045523(CHEBI:34151 | CHEMBL3310737)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of rabbit reticulocyte 15-LOX by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50045522(CHEBI:68947 | CHEMBL1378466)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human leukocyte 5-lipoxygenase by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50025735((5Z,8Z,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic a...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human leukocyte 5-lipoxygenase by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50045522(CHEBI:68947 | CHEMBL1378466)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human platelet 12-lipoxygenase by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Oryctolagus cuniculus (rabbit))
University Of California

Curated by ChEMBL
LigandPNGBDBM50045522(CHEBI:68947 | CHEMBL1378466)
Affinity DataIC50:  1.00E+5nMAssay Description:Inhibition of rabbit reticulocyte 15-LOX by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50045522(CHEBI:68947 | CHEMBL1378466)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human reticulocyte 15-lipoxygenase-1 by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50024458(5-oxo-ETE | CHEMBL18028 | ETE-5-Oxo)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human reticulocyte 15-lipoxygenase-2 by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50045523(CHEBI:34151 | CHEMBL3310737)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human reticulocyte 15-lipoxygenase-2 by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50025735((5Z,8Z,11Z,13E)-15-oxoicosa-5,8,11,13-tetraenoic a...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human reticulocyte 15-lipoxygenase-2 by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Homo sapiens (Human))
University Of California

Curated by ChEMBL
LigandPNGBDBM50045522(CHEBI:68947 | CHEMBL1378466)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human reticulocyte 15-lipoxygenase-2 by UV-visible spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed