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Found 24 Enz. Inhib. hit(s) with all data for entry = 50045224
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051031(CHEMBL2158745)
Affinity DataIC50:  0.400nMAssay Description:Inhibition of human HDAC1 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051031(CHEMBL2158745)
Affinity DataIC50:  3nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50309930(6-((1S,7R,10S,13R)-2,8,11,25-Tetraoxo-3,9,12,24-te...)
Affinity DataIC50:  5.5nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50309930(6-((1S,7R,10S,13R)-2,8,11,25-Tetraoxo-3,9,12,24-te...)
Affinity DataIC50:  9.10nMAssay Description:Inhibition of human HDAC1 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50309933(6-((5S,8R,11S,13aR)-4,7,10,13-Tetraoxo-5,8-dipenty...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051031(CHEMBL2158745)
Affinity DataIC50:  13nMAssay Description:Inhibition of mouse HDAC6 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051035(CHEMBL3309858)
Affinity DataIC50:  15nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051033(CHEMBL3309856)
Affinity DataIC50:  25nMAssay Description:Inhibition of human HDAC1 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50309933(6-((5S,8R,11S,13aR)-4,7,10,13-Tetraoxo-5,8-dipenty...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human HDAC1 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051034(CHEMBL3309857)
Affinity DataIC50:  25nMAssay Description:Inhibition of human HDAC1 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051033(CHEMBL3309856)
Affinity DataIC50:  26nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051032(CHEMBL3309855)
Affinity DataIC50:  31nMAssay Description:Inhibition of human HDAC1 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051034(CHEMBL3309857)
Affinity DataIC50:  31nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051035(CHEMBL3309858)
Affinity DataIC50:  37nMAssay Description:Inhibition of human HDAC1 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051032(CHEMBL3309855)
Affinity DataIC50:  41nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051036(CHEMBL3356087)
Affinity DataIC50:  43nMAssay Description:Inhibition of human HDAC4 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051036(CHEMBL3356087)
Affinity DataIC50:  43nMAssay Description:Inhibition of human HDAC1 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051035(CHEMBL3309858)
Affinity DataIC50:  140nMAssay Description:Inhibition of mouse HDAC6 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051033(CHEMBL3309856)
Affinity DataIC50:  230nMAssay Description:Inhibition of mouse HDAC6 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051032(CHEMBL3309855)
Affinity DataIC50:  240nMAssay Description:Inhibition of mouse HDAC6 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50309933(6-((5S,8R,11S,13aR)-4,7,10,13-Tetraoxo-5,8-dipenty...)
Affinity DataIC50:  340nMAssay Description:Inhibition of mouse HDAC6 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50309930(6-((1S,7R,10S,13R)-2,8,11,25-Tetraoxo-3,9,12,24-te...)
Affinity DataIC50:  410nMAssay Description:Inhibition of mouse HDAC6 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051034(CHEMBL3309857)
Affinity DataIC50:  490nMAssay Description:Inhibition of mouse HDAC6 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Mus musculus)
University Of Rajshahi

Curated by ChEMBL
LigandPNGBDBM50051036(CHEMBL3356087)
Affinity DataIC50:  570nMAssay Description:Inhibition of mouse HDAC6 expressed in HEK293T cells assessed as aminomethyl coumarin release using Ac-KGLGK(Ac)-MCA) substrate after 30 mins by FLIP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed