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Found 7 Enz. Inhib. hit(s) with all data for entry = 50046797
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Wakunaga Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50131703(CHEMBL3633520)
Affinity DataIC50:  174nMAssay Description:Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Wakunaga Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50131705(CHEMBL3633518)
Affinity DataIC50:  286nMAssay Description:Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Wakunaga Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50131702(CHEMBL3633521)
Affinity DataIC50:  411nMAssay Description:Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Wakunaga Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50131701(CHEMBL3633522)
Affinity DataIC50:  433nMAssay Description:Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Wakunaga Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50366826(DR-3355 | Floxacin | Iquix | LEVOFLOXACIN | Levaqu...)
Affinity DataIC50:  470nMAssay Description:Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Wakunaga Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50131704(CHEMBL3633519)
Affinity DataIC50:  553nMAssay Description:Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA gyrase subunit A/B(Escherichia coli (strain K12))
Wakunaga Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50131700(CHEMBL3633523)
Affinity DataIC50:  694nMAssay Description:Inhibition of Escherichia coli DNA gyrase preincubated for 5 mins at 37 degC before addition of relaxed pBR322 as substrate by supercoiling assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed