Compile Data Set for Download or QSAR
maximum 50k data
Found 28 Enz. Inhib. hit(s) with all data for entry = 7563
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM202553((E/Z)-2-cyano-3-(5-(1-cyclohexyl-1,6-dihydroimidaz...)
Affinity DataIC50:  0.127nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM202554((E/Z)-2-cyano-N,N-dimethyl-3-(5-(1-((1S,2R)-2-meth...)
Affinity DataIC50:  0.154nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  0.292nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  0.496nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  2.20nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3 [781-1124](Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  3.5nMAssay Description:In this ELISA-based kinase activity assay, a 96-well assay plate is coated with an artificial polypeptide serving as kinase substrate that contains t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  8.90nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3 [781-1124](Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM202553((E/Z)-2-cyano-3-(5-(1-cyclohexyl-1,6-dihydroimidaz...)
Affinity DataIC50:  9nMAssay Description:In this ELISA-based kinase activity assay, a 96-well assay plate is coated with an artificial polypeptide serving as kinase substrate that contains t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3 [781-1124](Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM202554((E/Z)-2-cyano-N,N-dimethyl-3-(5-(1-((1S,2R)-2-meth...)
Affinity DataIC50:  17nMAssay Description:In this ELISA-based kinase activity assay, a 96-well assay plate is coated with an artificial polypeptide serving as kinase substrate that contains t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM202552((E)-3-(5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]py...)
Affinity DataIC50:  19nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM202552((E)-3-(5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]py...)
Affinity DataIC50:  22nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3 [781-1124](Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM202552((E)-3-(5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]py...)
Affinity DataIC50:  51nMAssay Description:In this ELISA-based kinase activity assay, a 96-well assay plate is coated with an artificial polypeptide serving as kinase substrate that contains t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM202553((E/Z)-2-cyano-3-(5-(1-cyclohexyl-1,6-dihydroimidaz...)
Affinity DataIC50:  52nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3 [781-1124](Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM50426731(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]pyrrolo[2,3-...)
Affinity DataIC50:  63nMAssay Description:In this ELISA-based kinase activity assay, a 96-well assay plate is coated with an artificial polypeptide serving as kinase substrate that contains t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM202554((E/Z)-2-cyano-N,N-dimethyl-3-(5-(1-((1S,2R)-2-meth...)
Affinity DataIC50:  64nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM202552((E)-3-(5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]py...)
Affinity DataIC50:  78nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM202552((E)-3-(5-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]py...)
Affinity DataIC50:  113nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3 [781-1124](Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM202557((E)-3-(4-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]py...)
Affinity DataIC50:  226nMAssay Description:In this ELISA-based kinase activity assay, a 96-well assay plate is coated with an artificial polypeptide serving as kinase substrate that contains t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM202554((E/Z)-2-cyano-N,N-dimethyl-3-(5-(1-((1S,2R)-2-meth...)
Affinity DataIC50:  270nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM202553((E/Z)-2-cyano-3-(5-(1-cyclohexyl-1,6-dihydroimidaz...)
Affinity DataIC50:  346nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM202553((E/Z)-2-cyano-3-(5-(1-cyclohexyl-1,6-dihydroimidaz...)
Affinity DataIC50:  459nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3 [781-1124](Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM202555((E)-3-(3-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]py...)
Affinity DataIC50:  470nMAssay Description:In this ELISA-based kinase activity assay, a 96-well assay plate is coated with an artificial polypeptide serving as kinase substrate that contains t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3 [781-1124](Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM202556((E)-3-(3-(1-cyclohexyl-1,6-dihydroimidazo[4,5-d]py...)
Affinity DataIC50:  548nMAssay Description:In this ELISA-based kinase activity assay, a 96-well assay plate is coated with an artificial polypeptide serving as kinase substrate that contains t...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM202554((E/Z)-2-cyano-N,N-dimethyl-3-(5-(1-((1S,2R)-2-meth...)
Affinity DataIC50:  898nMAssay Description:A commercial assay by Reaction Biology Corp.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM202553((E/Z)-2-cyano-3-(5-(1-cyclohexyl-1,6-dihydroimidaz...)
Affinity DataKd:  360nMAssay Description:The assay is based on the displacement of a reporter probe by a test compound. Close proximity of the probe and the targeted kinase result in emissio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM202553((E/Z)-2-cyano-3-(5-(1-cyclohexyl-1,6-dihydroimidaz...)
Affinity DataKd:  69.7nMAssay Description:The assay is based on the displacement of a reporter probe by a test compound. Close proximity of the probe and the targeted kinase result in emissio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM202553((E/Z)-2-cyano-3-(5-(1-cyclohexyl-1,6-dihydroimidaz...)
Affinity DataKd:  242nMAssay Description:The assay is based on the displacement of a reporter probe by a test compound. Close proximity of the probe and the targeted kinase result in emissio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Eberhard Karls University Tuebingen

LigandPNGBDBM202553((E/Z)-2-cyano-3-(5-(1-cyclohexyl-1,6-dihydroimidaz...)
Affinity DataKd:  1.34nMAssay Description:The assay is based on the displacement of a reporter probe by a test compound. Close proximity of the probe and the targeted kinase result in emissio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed