Found 42 Enz. Inhib. hit(s) with all data for entry = 50000549 
Affinity DataKi: 0.109nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.154nMAssay Description:Positive allosteric modulation of human M4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in acetylcholine-induced calcium m...More data for this Ligand-Target Pair
Affinity DataKi: 0.221nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.274nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.301nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.308nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.325nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.368nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.383nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.458nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.501nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.548nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.627nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.658nMAssay Description:Displacement of [3H]U-69,593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 0.760nMAssay Description:Displacement of [3H]DPDPE from delta opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 0.833nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]U-69,593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 1.40nMAssay Description:Displacement of [3H]U-69,593 from human kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 2.5nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 3.90nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataKi: 4.5nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor in mouse whole brain without cerebellum membraneMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 6.30nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum membraneMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 20nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum membraneMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 31nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum membraneMore data for this Ligand-Target Pair
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Kitasato University
Curated by ChEMBL
Kitasato University
Curated by ChEMBL
Affinity DataKi: 34nMAssay Description:Displacement of [3H]U-69,593 from kappa opioid receptor in guinea pig cerebellum membraneMore data for this Ligand-Target Pair
Affinity DataEC50: 0.430nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by...More data for this Ligand-Target Pair
Affinity DataEC50: 0.540nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by...More data for this Ligand-Target Pair
Affinity DataEC50: 5.90nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by Eu...More data for this Ligand-Target Pair
Affinity DataEC50: 2.5nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by Eu...More data for this Ligand-Target Pair
Affinity DataEC50: 0.430nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by...More data for this Ligand-Target Pair
Affinity DataEC50: 404nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by...More data for this Ligand-Target Pair
Affinity DataEC50: 22nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by Eu...More data for this Ligand-Target Pair
Affinity DataEC50: 5.30nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by Eu...More data for this Ligand-Target Pair
Affinity DataEC50: 0.670nMAssay Description:Positive allosteric modulation of human M4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in acetylcholine-induced calcium m...More data for this Ligand-Target Pair
Affinity DataEC50: 1.20nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Affinity DataEC50: 98nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by...More data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by...More data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by...More data for this Ligand-Target Pair
Affinity DataEC50: 0.610nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by...More data for this Ligand-Target Pair
Affinity DataEC50: 1.40nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by...More data for this Ligand-Target Pair
