Compile Data Set for Download or QSAR
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Found 21 Enz. Inhib. hit(s) with all data for entry = 50000360
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247512(CHEBI:52279 | CHEMBL436524)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate after 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247526(CHEMBL4080916)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247525(CHEMBL4070279)
Affinity DataEC50:  8.28E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate after 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247526(CHEMBL4080916)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate after 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247527(CHEMBL4105160)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate after 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247528(CHEMBL4099866)
Affinity DataEC50:  1.47E+3nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate after 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247529(CHEMBL4084530)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate after 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247512(CHEBI:52279 | CHEMBL436524)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247530(CHEMBL374342)
Affinity DataEC50:  563nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247525(CHEMBL4070279)
Affinity DataEC50:  6.34E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247531(CHEMBL4097456)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247527(CHEMBL4105160)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247528(CHEMBL4099866)
Affinity DataEC50:  381nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247532(CHEMBL4081867)
Affinity DataEC50:  1.23E+3nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247529(CHEMBL4084530)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247528(CHEMBL4099866)
Affinity DataKd:  381nMAssay Description:Binding affinity to recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells by spectrofluorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247530(CHEMBL374342)
Affinity DataEC50:  2.02E+3nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate after 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247531(CHEMBL4097456)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate after 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247532(CHEMBL4081867)
Affinity DataEC50:  1.97E+3nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate after 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247524(CHEMBL4078465)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDNA topoisomerase 1(Homo sapiens (Human))
Ahmedabad University

Curated by ChEMBL
LigandPNGBDBM50247524(CHEMBL4078465)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of recombinant human topoisomerase-1 expressed in baculovirus infected sf9 cells using supercoiled pBS SK(+) DNA as substrate after 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed