TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 4.70nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP as substrate measured after 30 mins by scintillation proximity assayMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 4.80nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 72nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 81nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 310nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 570nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of human PDE2 using c[8-3H]cAMP or c[8-3H]cGMP as substrate measured after 10 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 1.94E+3nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 2.63E+3nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 3.79E+3nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 3.91E+3nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 3.99E+3nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 4.28E+3nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 4.32E+3nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 5.46E+3nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 5.94E+3nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 7.27E+3nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of PDE9 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 3.23E+4nMAssay Description:Inhibition of PDE9 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: 4.04E+4nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of PDE2 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of PDE4 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of PDE5 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of PDE10 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of PDE1 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of PDE4 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of PDE5 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of PDE10 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
TargetDual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A/1B/1C(Homo sapiens (Human))
Changzhou University
Curated by ChEMBL
Changzhou University
Curated by ChEMBL
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of PDE1 (unknown origin) using [3H]cAMP or [3H]cGMP as substrate measured after 30 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair