TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 20nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 25nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 84nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 87nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 105nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 115nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 125nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 171nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 298nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 535nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 555nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 639nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 923nMAssay Description:Inhibition of human PDE2A using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of human GST-tagged PDE3A (484 to end residues) using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of human PDE2A using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of human PDE2A using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 1.78E+3nMAssay Description:Inhibition of human full-length PDE4D2 expressed in Sf9 insect cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 1.79E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant human N-terminal His-tagged PDE10A2 expressed in HEK293 cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 1.86E+3nMAssay Description:Inhibition of human PDE2A using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 2.16E+3nMAssay Description:Inhibition of human PDE2A using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 2.98E+3nMAssay Description:Inhibition of human full-length PDE4D2 expressed in Sf9 insect cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 3.01E+3nMAssay Description:Inhibition of human PDE2A using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 3.52E+3nMAssay Description:Inhibition of human PDE2A using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 4.22E+3nMAssay Description:Inhibition of human full-length PDE4D2 expressed in Sf9 insect cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 4.27E+3nMAssay Description:Inhibition of human full-length PDE4D2 expressed in Sf9 insect cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 4.27E+3nMAssay Description:Inhibition of human full-length PDE4D2 expressed in Sf9 insect cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 4.89E+3nMAssay Description:Inhibition of human PDE2A using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 4.94E+3nMAssay Description:Inhibition of human GST-tagged PDE3A (484 to end residues) using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 5.39E+3nMAssay Description:Inhibition of human PDE2A using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 5.54E+3nMAssay Description:Inhibition of human full-length PDE4D2 expressed in Sf9 insect cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 6.13E+3nMAssay Description:Inhibition of human full-length PDE4D2 expressed in Sf9 insect cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 7.07E+3nMAssay Description:Inhibition of human GST-tagged PDE3A (484 to end residues) using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 7.47E+3nMAssay Description:Inhibition of human GST-tagged PDE3A (484 to end residues) using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 7.84E+3nMAssay Description:Inhibition of human GST-tagged PDE3A (484 to end residues) using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 7.85E+3nMAssay Description:Inhibition of human full-length PDE4D2 expressed in Sf9 insect cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 7.85E+3nMAssay Description:Inhibition of human GST-tagged PDE3A (484 to end residues) using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of human GST-tagged PDE3A (484 to end residues) using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 8.52E+3nMAssay Description:Inhibition of human GST-tagged PDE3A (484 to end residues) using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 8.92E+3nMAssay Description:Inhibition of human full-length PDE4D2 expressed in Sf9 insect cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Homo sapiens (Human))
Abbvie Deutschland
Curated by ChEMBL
Abbvie Deutschland
Curated by ChEMBL
Affinity DataIC50: 9.54E+3nMAssay Description:Inhibition of human full-length PDE4D2 expressed in Sf9 insect cells using cAMP as substrate measured after 60 minsMore data for this Ligand-Target Pair