Compile Data Set for Download or QSAR
maximum 50k data
Found 23 Enz. Inhib. hit(s) with all data for entry = 50009015
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50152124(CHEMBL3782004)
Affinity DataIC50:  5nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50117930((4-{1-[2-(6-Methyl-pyridin-2-yl)-ethyl]-piperidine...)
Affinity DataIC50:  7.80nMAssay Description:Inhibition of fluorescently labeled tracer binding to human ERG by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50524490(CHEMBL4561244)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50524491(CHEMBL4446950)
Affinity DataIC50:  400nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50524489(CHEMBL4541864)
Affinity DataIC50:  800nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50524488(CHEMBL4589188)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50524493(CHEMBL4448755)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50524487(CHEMBL1232596)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50324898(3-(2-amino-5-chloro-1H-benzimidazol-1-yl)propan-1-...)
Affinity DataIC50:  2.80E+4nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM7960(1H-1,3-benzodiazol-2-amine | 2-Aminobenzimidazole ...)
Affinity DataIC50:  4.40E+4nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50372980(CHEMBL404150)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50524492(CHEMBL4476663)
Affinity DataIC50:  1.23E+5nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM16223(1H-pyrrolo[2,3-b]pyridine | 7-azaindole | compound...)
Affinity DataIC50:  1.32E+5nMAssay Description:Inhibition of recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) cells using dGTP as substrate incubated for 15 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50524488(CHEMBL4589188)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of BACE1 (unknown origin) using HiLyte Fluo488/QXL-520 as substrate by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50524490(CHEMBL4561244)
Affinity DataIC50: >2.00E+5nMAssay Description:Inhibition of BACE1 (unknown origin) using HiLyte Fluo488/QXL-520 as substrate by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM16223(1H-pyrrolo[2,3-b]pyridine | 7-azaindole | compound...)
Affinity DataKd:  9.60E+4nMAssay Description:Binding affinity to recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as dissociation constant by isother...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50324898(3-(2-amino-5-chloro-1H-benzimidazol-1-yl)propan-1-...)
Affinity DataKd:  1.50E+4nMAssay Description:Binding affinity to recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as dissociation constant by isother...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50524489(CHEMBL4541864)
Affinity DataKd:  2.40E+3nMAssay Description:Binding affinity to recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as dissociation constant by isother...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50524491(CHEMBL4446950)
Affinity DataKd:  700nMAssay Description:Binding affinity to recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as dissociation constant by isother...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50524488(CHEMBL4589188)
Affinity DataKd:  1.30E+3nMAssay Description:Binding affinity to recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as dissociation constant by isother...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM7960(1H-1,3-benzodiazol-2-amine | 2-Aminobenzimidazole ...)
Affinity DataKd:  1.80E+4nMAssay Description:Binding affinity to recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as dissociation constant by isother...More data for this Ligand-Target Pair
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50524490(CHEMBL4561244)
Affinity DataKd:  100nMAssay Description:Binding affinity to recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as dissociation constant by isother...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetOxidized purine nucleoside triphosphate hydrolase(Homo sapiens (Human))
University Of Zurich

Curated by ChEMBL
LigandPNGBDBM50524487(CHEMBL1232596)
Affinity DataKd:  1.50E+4nMAssay Description:Binding affinity to recombinant His-tagged MTH1 (unknown origin) expressed in Escherichia coli BL21(DE3) assessed as dissociation constant by isother...More data for this Ligand-Target Pair