Compile Data Set for Download or QSAR
maximum 50k data
Found 67 Enz. Inhib. hit(s) with all data for entry = 50008237
TargetAcetylcholine receptor subunit epsilon(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516992(CHEMBL4473371)
Affinity DataKi:  3.10nMAssay Description:Inhibition of AChE (unknown origin) by spectrophotometric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit epsilon(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataKi:  152nMAssay Description:Inhibition of AChE (unknown origin) by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit epsilon(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516960(CHEMBL4435544)
Affinity DataIC50:  6nMAssay Description:Inhibition of AChE (unknown origin) after 2 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516960(CHEMBL4435544)
Affinity DataIC50:  6nMAssay Description:Inhibition of BuChE (unknown origin) after 2 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516959(CHEMBL4471876)
Affinity DataIC50:  27nMAssay Description:Inhibition of BuChE (unknown origin) after 2 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit epsilon(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516959(CHEMBL4471876)
Affinity DataIC50:  27nMAssay Description:Inhibition of AChE (unknown origin) after 2 minsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit epsilon(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516976(CHEMBL4518438)
Affinity DataIC50:  47nMAssay Description:Inhibition of AChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516977(CHEMBL4518992)
Affinity DataIC50:  49nMAssay Description:Inhibition of BuChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516975(CHEMBL4514263)
Affinity DataIC50:  49nMAssay Description:Inhibition of BuChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516974(CHEMBL4516351)
Affinity DataIC50:  56nMAssay Description:Inhibition of BuChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit epsilon(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516974(CHEMBL4516351)
Affinity DataIC50:  57nMAssay Description:Inhibition of AChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit epsilon(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516977(CHEMBL4518992)
Affinity DataIC50:  58nMAssay Description:Inhibition of AChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit epsilon(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516975(CHEMBL4514263)
Affinity DataIC50:  62nMAssay Description:Inhibition of AChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516976(CHEMBL4518438)
Affinity DataIC50:  70nMAssay Description:Inhibition of BuChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit epsilon(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516963(CHEMBL2376519)
Affinity DataIC50:  82nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit epsilon(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516982(CHEMBL4447626)
Affinity DataIC50:  88nMAssay Description:Inhibition of AChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516950(CHEMBL4544630)
Affinity DataIC50:  94nMAssay Description:Inhibition of BuChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit epsilon(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516950(CHEMBL4544630)
Affinity DataIC50:  97nMAssay Description:Inhibition of AChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516991(CHEMBL4466253)
Affinity DataIC50:  117nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured after 15...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516982(CHEMBL4447626)
Affinity DataIC50:  125nMAssay Description:Inhibition of BuChE (unknown origin) by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM167925((1-(2-Chlorobenzyl)-1H-1,2,3-triazol-4-yl)methyl 2...)
Affinity DataIC50:  180nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured after 6 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM8961(1,2,3,4-tetrahydro-9-acridinamine | 1,2,3,4-tetrah...)
Affinity DataIC50:  350nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured after 6 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50004000((3aS,8aR)-1,3a,8-trimethyl-1,2,3,3a,8,8a-hexahydro...)
Affinity DataIC50:  850nMAssay Description:Inhibition of BuChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516952(CHEMBL4465307)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 3 mins followed by substrate additionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit epsilon(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516970(CHEMBL4456791)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human AChE using acetylthiocholine iodide as substrate after 10 secs measured at 30 s intervals for two minutes by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit epsilon(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516985(CHEMBL4544034)
Affinity DataIC50:  2.10E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit epsilon(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM10404((1S,12S,14R)-9-methoxy-4-methyl-11-oxa-4-azatetrac...)
Affinity DataIC50:  2.66E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetAcetylcholine receptor subunit epsilon(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516966(CHEMBL4452517)
Affinity DataIC50:  2.72E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit epsilon(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516965(CHEMBL4458943)
Affinity DataIC50:  3.06E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516984(CHEMBL4476479)
Affinity DataIC50:  3.29E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 3 mins followed by substrate additionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516955(CHEMBL4439610)
Affinity DataIC50:  3.29E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 3 mins followed by substrate additionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516956(CHEMBL4593774)
Affinity DataIC50:  3.29E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 3 mins followed by substrate additionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516957(CHEMBL4520853)
Affinity DataIC50:  3.29E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 3 mins followed by substrate additionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516987(CHEMBL4437630)
Affinity DataIC50:  3.29E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 3 mins followed by substrate additionMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516986(CHEMBL4461294)
Affinity DataIC50:  4.52E+3nMAssay Description:Inhibition of BuChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516980(CHEMBL4571452)
Affinity DataIC50:  4.52E+3nMAssay Description:Inhibition of BuChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516951(CHEMBL4527996)
Affinity DataIC50:  4.52E+3nMAssay Description:Inhibition of BuChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516979(CHEMBL4452614)
Affinity DataIC50:  4.52E+3nMAssay Description:Inhibition of BuChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516981(CHEMBL4532230)
Affinity DataIC50:  4.52E+3nMAssay Description:Inhibition of BuChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516993(CHEMBL4521999)
Affinity DataIC50:  5.31E+3nMAssay Description:Inhibition of BuChE (unknown origin) using butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit epsilon(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516964(CHEMBL4573754)
Affinity DataIC50:  6.37E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataIC50:  6.39E+3nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) self aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516954(CHEMBL4451075)
Affinity DataIC50:  7.30E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 3 mins followed by substrate additionMore data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit epsilon(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516989(CHEMBL4590975)
Affinity DataIC50:  8.00E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAmyloid-beta precursor protein(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516988(CHEMBL4522050)
Affinity DataIC50:  8.07E+3nMAssay Description:Inhibition of amyloid beta (1 to 42) (unknown origin) self aggregationMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516948(CHEMBL4547910)
Affinity DataIC50:  8.55E+3nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in baculovirus-expression system using Rh-EVNLDAEFK-Quencher substrate after 90 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516958(CHEMBL4556299)
Affinity DataIC50:  1.14E+4nMAssay Description:Inhibition of BACE1 (unknown origin) expressed in baculovirus-expression system using Rh-EVNLDAEFK-Quencher substrate after 90 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholine receptor subunit epsilon(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516949(CHEMBL4555431)
Affinity DataIC50:  1.23E+4nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Electrophorus electricus (Electric eel))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50022775((m-Hydroxyphenyl)trimethylammonium dimethylcarbama...)
Affinity DataIC50:  1.63E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition measured after 15...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCholinesterase(Homo sapiens (Human))
Wuhan Institute Of Technology

Curated by ChEMBL
LigandPNGBDBM50516961(CHEMBL4471734)
Affinity DataIC50:  1.80E+4nMAssay Description:Inhibition of BuChE (unknown origin) using butyrylthiocholine iodide as substrate after 15 mins by Ellman's methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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