Found 6 Enz. Inhib. hit(s) with all data for entry = 50013297 TargetHistone deacetylase 2(Homo sapiens (Human))
Beijing University Of Chemical Technology
Curated by ChEMBL
Beijing University Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human HDAC2 using FLUOR-DE-LYS-Green as substrate incubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
TargetHistone deacetylase 2(Homo sapiens (Human))
Beijing University Of Chemical Technology
Curated by ChEMBL
Beijing University Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of recombinant human HDAC2 using FLUOR-DE-LYS-Green as substrate incubated for 10 mins followed by substrate addition and measured after 3...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Beijing University Of Chemical Technology
Curated by ChEMBL
Beijing University Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 71nMAssay Description:Inhibition of recombinant human HDAC1 using SIRT1 as substrate incubated for 10 mins followed by substrate addition and measured after 30 mins by flu...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Beijing University Of Chemical Technology
Curated by ChEMBL
Beijing University Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 110nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged CDK2/CyclinA2 expressed in baculovirus infected Sf21 cells using histone H1 as substrate incuba...More data for this Ligand-Target Pair
3D Structure (crystal)TargetHistone deacetylase 1(Homo sapiens (Human))
Beijing University Of Chemical Technology
Curated by ChEMBL
Beijing University Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant human HDAC1 using SIRT1 as substrate incubated for 10 mins followed by substrate addition and measured after 30 mins by flu...More data for this Ligand-Target Pair
TargetCyclin-A2/Cyclin-dependent kinase 2(Homo sapiens (Human))
Beijing University Of Chemical Technology
Curated by ChEMBL
Beijing University Of Chemical Technology
Curated by ChEMBL
Affinity DataIC50: 800nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged CDK2/CyclinA2 expressed in baculovirus infected Sf21 cells using histone H1 as substrate incuba...More data for this Ligand-Target Pair
