TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 2.10nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 2.60nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 4.20nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 6.70nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 9.80nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 35nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 46nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 160nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 921nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 1.24E+3nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 1.68E+3nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 4.66E+3nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells at holding potential of -80 mV by patch clamp methodMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells at holding potential of -80 mV by patch clamp methodMore data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 9.69E+3nMAssay Description:Inhibition of human liver microsome CYP2C9 using diclofenac as substrate preincubated for 10 mins followed by substrate and NADPH addition and measur...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human His-tagged full length BTK expressed in baculovirus expression system using TK1 as substrate incubated for 60 mins by...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 3.35E+4nMAssay Description:Inhibition of human liver microsome CYP2C19 using S-mephenytoin as substrate preincubated for 10 mins followed by substrate and NADPH addition and me...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 3.73E+4nMAssay Description:Inhibition of human liver microsome CYP3A4 using midazolam as substrate preincubated for 10 mins followed by substrate and NADPH addition and measure...More data for this Ligand-Target Pair
TargetCytochrome P450 2C9(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 3.96E+4nMAssay Description:Inhibition of human liver microsome CYP2C9 using diclofenac as substrate preincubated for 10 mins followed by substrate and NADPH addition and measur...More data for this Ligand-Target Pair
TargetCytochrome P450 3A4(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 4.08E+4nMAssay Description:Inhibition of human liver microsome CYP3A4 using midazolam as substrate preincubated for 10 mins followed by substrate and NADPH addition and measure...More data for this Ligand-Target Pair
TargetCytochrome P450 2C19(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: 4.39E+4nMAssay Description:Inhibition of human liver microsome CYP2C19 using S-mephenytoin as substrate preincubated for 10 mins followed by substrate and NADPH addition and me...More data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human liver microsome CYP1A2 using phenacetin as substrate preincubated for 10 mins followed by substrate and NADPH addition and measur...More data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human liver microsome CYP2D6 using dextromethorphan as substrate preincubated for 10 mins followed by substrate and NADPH addition and ...More data for this Ligand-Target Pair
TargetCytochrome P450 2D6(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human liver microsome CYP2D6 using dextromethorphan as substrate preincubated for 10 mins followed by substrate and NADPH addition and ...More data for this Ligand-Target Pair
TargetCytochrome P450 1A2(Homo sapiens (Human))
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Hubei Bio-Pharmaceutical Industrial Technological Institute
Curated by ChEMBL
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human liver microsome CYP1A2 using phenacetin as substrate preincubated for 10 mins followed by substrate and NADPH addition and measur...More data for this Ligand-Target Pair