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Found 8 Enz. Inhib. hit(s) with all data for entry = 50017347
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Hunan University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM13216(BMS-354825 | CHEMBL1421 | DASATINIB | N-(2-Chloro-...)
Affinity DataKi:  0.0160nMAssay Description:Binding affinity to Src (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMedDrugBank

TargetSphingosine kinase 2(Homo sapiens (Human))
Hunan University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50312869(4-(4-(4-chlorophenyl)thiazol-2-ylamino)phenol | CH...)
Affinity DataKi:  7.90E+3nMAssay Description:Binding affinity to Sphk2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSphingosine kinase 1(Homo sapiens (Human))
Hunan University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50312869(4-(4-(4-chlorophenyl)thiazol-2-ylamino)phenol | CH...)
Affinity DataKi:  1.60E+4nMAssay Description:Binding affinity to Sphk1 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
TargetHistone deacetylase(Homo sapiens (Human))
Hunan University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50601389(CHEMBL5189571)
Affinity DataIC50:  120nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHistone deacetylase(Homo sapiens (Human))
Hunan University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  250nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract measured after 30 mins by fluorescence based assayMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Hunan University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50601390(CHEMBL5177698)
Affinity DataIC50:  780nMAssay Description:Inhibition of CDK2 in human A549 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 3(Homo sapiens (Human))
Hunan University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50601390(CHEMBL5177698)
Affinity DataIC50:  870nMAssay Description:Inhibition of CDK3 in human A549 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Hunan University Of Science And Technology

Curated by ChEMBL
LigandPNGBDBM50601390(CHEMBL5177698)
Affinity DataIC50:  1.47E+3nMAssay Description:Inhibition of CDK1 in human A549 cellsMore data for this Ligand-Target Pair
In DepthDetails PubMed